66749-60-8 Usage
Uses
Used in Pharmaceutical Industry:
(+)-DIACETYL-D-TARTARIC ACID is used as a chiral resolving agent for the resolution of enantiomers, which is crucial for the development of single-enantiomer drugs with improved efficacy and reduced side effects.
(+)-DIACETYL-D-TARTARIC ACID is also used as a chiral auxiliary in synthesis reactions, aiding in the production of chiral catalysts that are essential for the synthesis of various pharmaceutical compounds.
Used in Synthesis of Pharmaceuticals:
(+)-DIACETYL-D-TARTARIC ACID is used as a key intermediate in the synthesis of pharmaceuticals, contributing to the development of new and improved drugs with enhanced therapeutic properties.
Used in Agricultural Chemicals:
(+)-DIACETYL-D-TARTARIC ACID is used in the synthesis of chiral agricultural chemicals, helping to create more effective and targeted pest control solutions.
Used in Flavor Industry:
(+)-DIACETYL-D-TARTARIC ACID is used in the synthesis of chiral flavors, enhancing the taste and aroma profiles of various food and beverage products.
Used in Food Industry as an Acidulent:
(+)-DIACETYL-D-TARTARIC ACID is used as an acidulant in the food industry, providing a tart flavor to various food products and contributing to their overall taste profile.
Used in Food Industry as a Sequestrant:
(+)-DIACETYL-D-TARTARIC ACID is used as a sequestrant in the food industry, helping to prevent the oxidation of fats and oils, thereby extending the shelf life of food products.
Check Digit Verification of cas no
The CAS Registry Mumber 66749-60-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,7,4 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 66749-60:
(7*6)+(6*6)+(5*7)+(4*4)+(3*9)+(2*6)+(1*0)=168
168 % 10 = 8
So 66749-60-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10O8/c1-3(9)15-5(7(11)12)6(8(13)14)16-4(2)10/h5-6H,1-2H3,(H,11,12)(H,13,14)/t5-,6-/m0/s1
66749-60-8Relevant academic research and scientific papers
Synthesis and anti-HIV activity of new C2 symmetric derivatives designed as HIV-1 protease inhibitors
Pecanha, Emerson P.,Figueiredo, Luciana J.O.,Brindeiro, Rodrigo M.,Tanuri, Amilcar,Calazans, Alexandre R.,Antunes
, p. 149 - 157 (2007/10/03)
The synthesis of several new anti-HIV-1 compounds is described. The new compounds contain a C2 symmetry axis and a dihidroxyethylene moiety based on the D-tartaric acid back bone. The synthesis of these compounds was achieved in 36-69% overall
Synthesis and pharmacological activity of stereoisomers of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester
Muto,Kuroda,Kawato,Karasawa,Kubo,Nakamizo
, p. 1662 - 1665 (2007/10/02)
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester 1, a highly potent calcium antagonist, was separated into stereo- and optical isomers to investigate the differences of antihypertensive activities between them. Fractional crystallization of the hydrochlorides of 1 gave α- and β-diasterioisomers. The α-isomer (benidipine hydrochloride, KW-3049) showed very strong hypotensive effect, but little activity was observed in the β-isomer. From optically resolved 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridi necarboxylic acids 2, and 1-benzyl-3-piperidinols 3, four optical isomers of 1 were synthesized, and their absolute configurations were deduced. The hypotensive activity of (+)-α, namely (S)-(S)-1, was 30 to 100 times stronger than that of (-)-α in intravenously administered spontaneously hypertensive rats.
