66773-30-6

Upstream product

• 15862-94-9 1-(chloromethyl)-4,5-dimethoxy-2-nitrobenzene 
• 609-09-6 Diethyl ketomalonate 
• 20357-25-9 6-nitroveratraldehyde 
• 105-53-3 diethyl malonate 
• 24844-72-2 (4,5-dimethoxy-2-nitro-benzylidene)-malonic acid diethyl ester 

Downstream Products

• 1387641-91-9 4-chloro-3-(6,7-dimethoxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxamido)benzoic acid 
• 1387641-55-5 4-chloro-3-[(6,7-dimethoxy-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carbonyl)-amino]-benzoic acid methyl ester 
• 1387641-56-6 3-[(6,7-dimethoxy-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carbonyl)-amino]-4-methyl-benzoic acid methyl ester 
• 1387641-57-7 6,7-Dimethoxy-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carboxylic acid (5-benzylcarbamoyl-2-chloro-phenyl)-amide 
• 1387641-58-8 6,7-dimethoxy-2-oxo-1,2,3,4-tetrahydro-quinoline-3-carboxylic acid (5-benzylcarbamoyl-2-methyl-phenyl)amide 

Relevant academic research and scientific papers

Synthesis, biological activity and structure-activity relationship of 4,5-dimethoxybenzene derivatives inhibitor of rhinovirus 14 infection

Human rhinoviruses are a common cause of respiratory infections, and thus constitute an important target for medicinal chemistry. Still, no drug has been approved for clinical use. We report herein the discovery of dibenzenic derivatives with potent and s

CARBOXYLIC ACID ARYL AMIDES

Compounds of formula and pharmaceutically acceptable salts thereof are described, as well as the pharmaceutical compositions containing said compounds and their pharmaceutically acceptable salts, and the use of said compounds and pharmaceutical compositions for the treatment, control or amelioration of proliferative diseases, including cancer.