66792-71-0Relevant academic research and scientific papers
An efficient synthesis of α-acyloxyketone by Cu(acac)2-catalyzed insertion reaction of α-diazoketone to carboxylic acid
Shinada, Tetsuro,Kawakami, Tadashi,Sakai, Hiroshi,Takada, Ichinori,Ohfune, Yasufumi
, p. 3757 - 3760 (1998)
An efficient insertion reaction of α-diazoketone to various carboxylic acids was achieved by using Cu(acac)2 as a catalyst. Treatment of the diazo compound with a carboxylic acid (1.2 equiv) in the presence of Cu(acac)2 (0.1 equiv) at room temperature afforded the corresponding ketoester in good yield. Various kinds of functional groups were tolerated under the reaction conditions.
