667925-66-8Relevant articles and documents
Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: Synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives
Yoshida, Masato,Mori, Akira,Kotani, Etsuo,Oka, Masahiro,Makino, Haruhiko,Fujita, Hisashi,Ban, Junko,Ikeda, Yukihiro,Kawamoto, Tomohiro,Goto, Mika,Kimura, Hiroyuki,Baba, Atsuo,Yasuma, Tsuneo
, p. 1430 - 1440 (2011/05/12)
As part of our research for novel calcium-sensing receptor (CaSR) antagonists that can function as oral bone anabolic agents, we recently reported the discovery of a tetrahydropyrazolopyrimidine derivative featuring adamantyl group 1b with potent CaSR ant