667939-87-9Relevant academic research and scientific papers
Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors
Birch, Helen L.,Buckley, George M.,Davies, Natasha,Dyke, Hazel J.,Frost, Elizabeth J.,Gilbert, Philip J.,Hannah, Duncan R.,Haughan, Alan F.,Madigan, Michael J.,Morgan, Trevor,Pitt, William R.,Ratcliffe, Andrew J.,Ray, Nicholas C.,Richard, Marianna D.,Sharpe, Andrew,Taylor, Alicia J.,Whitworth, Justine M.,Williams, Sophie C.
, p. 5335 - 5339 (2007/10/03)
The synthesis and biological activity of a novel series of 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones are described. Some of these compounds were found to be potent inhibitors of inosine 5′-monophosphate dehydrogenase type II (IMPDH II).
QUINAZOLINONE DERIVATIVES
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Page 46, (2008/06/13)
A compound of formula (1): wherein: X is an oxygen or sulfur atom; R1 is an aliphatic, cycloaliphatic or cycloalkyl-alkyl-group; R2 is an optionally substituted heteroaromatic group or a -CN group; R3 is a group -(Alk
