667940-67-2Relevant academic research and scientific papers
Synthesis and structure-activity relationships of thieno[2,3-b]pyrroles as antagonists of the GnRH receptor
Arnould, Jean Claude,Delouvrie, Benedicte,Boutron, Pascal,Dossetter, Al G.,Foote, Kevin M.,Hamon, Annie,Hancox, Urs,Harris, Craig S.,Hutton, Mike,Lamorlette, Maryannick,Matusiak, Zbigniew
, p. 6448 - 6454 (2008/09/17)
A new class of small-molecule GnRH antagonists, the thieno[2,3-b]pyrroles, was designed. Herein, the synthesis and structure-activity relationships are described. Substitution at the C4 position was investigated; during this study, it was observed that in
PYRROLE DERIVATIVES AS GONADOTROPIN RELEASING HORMONE (GNRH) ANTAGONISTS
-
, (2008/06/13)
The invention relates to a group of novel thieno-pyrrole compounds of formula (I) wherein: R1,R2, R3, R4 M, and R5 are as defined in the specification, as inter alia, gonadotrophin releasing hor
THIENO-PYRROLE COMPOUNDS AS ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE
-
Page 55; 56, (2010/11/30)
The invention relates to a group of novel thieno-pyrrole compounds of Formula (I), wherein: R1, R2, R4, R5, R6, R6a, R7, R8, A and B are as defined in the specificatio
