66840-50-4

Upstream product

• 2062-98-8 perfluoro(2-propoxypropionyl) fluoride 
• 205876-57-9 3-((2R,6S)-2,6-Dimethyl-morpholin-4-yl)-2-methyl-propionic acid methyl ester 
• 141-91-3 cis-2,6-dimethylmorpholine 
• 353-36-6 1-fluoroethane 
• 422-61-7 perfluoropropanoyl fluoride 
• 17648-12-3 (Z)-1-Ethoxy-1,2,3,3,3-pentafluoro-propene 
• 205876-56-8 3-((2R,6S)-2,6-Dimethyl-morpholin-4-yl)-propionic acid methyl ester 
• 205876-55-7 methyl [(2R,6S)-2,6-dimethyl-4-morpholinyl]acetate 

Relevant academic research and scientific papers

Catalytic process for making hydrofluoroethers

Briefly, in one aspect, this invention provides a catalytic method of preparation of primary and secondary hydrofluoroethers, the process comprising reacting a fluorinated precursor material and an alkylating agent in the presence of a Lewis acid catalyst or a mixture comprising Lewis acid and Bronsted acid catalysts.

Technology for the preparation of perfluoro-organic compounds

Fluorination by elemental fluorine of fluorine-containing alkenes, alkanes, ethers and tertiary amines was investigated, aimed at obtaining the perfluorinated analogs. The factors affecting yield of the target compounds were studied. Elements of technology were elucidated.

Electrochemical fluorination of N-containing carboxylic acids: Part 5. Fluorination of the methyl esters of cis-2,6-dimethylmorpholino-group substituted carboxylic acids

Cis-2,6-dimethylmorpholine and its derivatives having an ester group were subjected to electrochemical fluorination. The electrochemical fluorination of cis-2,6-dimethylmorpholine afforded only a small quantity of F-(N-fluoro-2,6-dimethyl-morpholine), whereas the N-(meth-oxycarbonylalkyl)-substituted cis-2,6-dimethyl-morpholines gave the corresponding F-acid fluorides in fair yields. Cis-and trans-isomerization on two methyl substituents of the morpholine ring occurred through electrochemical fluorination of pure cis-2,6-dimethylmorpholine to give a 1:0.25-0.5 mixture of cis- and trans-isomers having a F-2,6-dimethylmorpholino-moiety. The formation of a seven-membered ring expanded product was confirmed as a by-product in the fluorination of methyl cis-2,6-dimethylmorpholino-acetate. Spectroscopic data as well as physical properties of new nitrogen-containing F-carboxylic acids are presented.

DIRECT GAS-PHASE CATALYTIC FLUORINATION OF PARTIALLY FLUORINATED ORGANIC COMPOUNDS

The fluorination of a wide range of polyfluorinated organic compounds with molecular fluorine in the gas phase in a layer of NiF2/support as catalyst was investigated.It was shown that the selectivity of fluorination of the series of fluoroolefins, acid fluorides, polyfluoroalkanes, and hydrogen-containing ethers can be greatly increased.The developed method was used on an industrial scale in the production of perfluorinated liquids.