668486-08-6

Upstream product

• 5650-07-7 3-methyl-1-phenyl-but-2-en-1-one 
• 667930-84-9 (5S)-(-)-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[ 1,5-a]-pyrimidine-3-carboxylic acid 
• 1268251-96-2 ethyl (5S)-7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 1268168-26-8 3-(4-methylphenyl)pentan-3-amine hydrochloride 
• 667920-79-8 ethyl 7,7-dimethyl-5-phenyl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate 
• 1260243-53-5 ethyl 7,7-dimethyl-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carboxylate 

Relevant academic research and scientific papers

Discovery of novel and potent orally active calcium-sensing receptor antagonists that stimulate pulselike parathyroid hormone secretion: Synthesis and structure-activity relationships of tetrahydropyrazolopyrimidine derivatives

As part of our research for novel calcium-sensing receptor (CaSR) antagonists that can function as oral bone anabolic agents, we recently reported the discovery of a tetrahydropyrazolopyrimidine derivative featuring adamantyl group 1b with potent CaSR ant