66853-76-7Relevant academic research and scientific papers
Preparation and antitubercular activities of alkylated amino alcohols and their glycosylated derivatives
Taveira, Aline F.,Hyaric, Mireille Le,Reis, Elaine F.C.,Araujo, Debora P.,Ferreira, Ana Paula,de Souza, Maria Aparecida,Alves, Livia L.,Lourenco, Maria C.S.,Vicente, Felipe Rodrigues C.,de Almeida, Mauro V.
, p. 7789 - 7794 (2007)
A series of N- and C-alkylated amino alcohols and of their protected galactopyranosyl derivatives was synthesized and evaluated for antitubercular activity. Five of these compounds displayed good activity, with a MIC below 12.5 μg/mL. The presence of the carbohydrate slightly affected the antibacterial activity.
