6690-41-1

Basic information

• Product Name: Benzoic acid, N-[[2,6-dichloro-3-(trifluoromethyl)phenyl]amino]- (9CI)
• Synonyms: Benzoic acid, N-[[2,6-dichloro-3-(trifluoromethyl)phenyl]amino]- (9CI)
• CAS NO: 6690-41-1
• Molecular Formula: C₁₄H₈Cl₂F₃NO₂
• Molecular Weight: 350.1200296
• Mol File: 6690-41-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 185.0-186.5 °C
• Boiling Point: 387.0±42.0 °C(Predicted)
• Appearance: /
• Density: 1.553±0.06 g/cm3(Predicted)
• PKA: 3.56±0.36(Predicted)
• CAS DataBase Reference: Benzoic acid, N-[[2,6-dichloro-3-(trifluoromethyl)phenyl]amino]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, N-[[2,6-dichloro-3-(trifluoromethyl)phenyl]amino]- (9CI)(6690-41-1)
• EPA Substance Registry System: Benzoic acid, N-[[2,6-dichloro-3-(trifluoromethyl)phenyl]amino]- (9CI)(6690-41-1)

Safety Data

• Hazardous Substances Data: 6690-41-1(Hazardous Substances Data)

Upstream product

• 6656-72-0 2,6-dichloro-3-trifluoromethyl aniline 
• 16497-87-3 potassium o-bromobenzoate 

Relevant articles and documents

Structure-activity relationships in a series of anti-inflammatory N-arylanthranilic acids

A large series of N-arylanthranilic acids has been prepared. Many of these compounds show high anti-inflammatory activity as measured by the anti-UV-erythema test. From this series have come the clinically useful nonsteroidal anti-inflammatory agents, flufenamic acid (Arlef), mefenamic acid (Ponstel), and the latest and most potent agent, N-(2,6-dichloro-m-tolyl)anthranilic acid (meclofenamic acid, Meclomen = the sodium salt). The structure-activity relationships of this series is discussed and a graphical representation is presented which allows the prediction of activity of new agents.