669003-32-1

Upstream product

• 922-67-8 propynoic acid methyl ester 
• 342901-70-6 (2R,4R,5R)-4-((R)-1-Benzyloxy-2-[1,3]dithian-2-yl-ethyl)-2-phenyl-[1,3]dioxan-5-ol 
• 100-39-0 benzyl bromide 
• 119943-96-3 Methyl 3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-arabino-hexopyranoside 
• 2774-19-8 (2R,4aR,6S,7S,8R,8aR)-8-Benzyloxy-6-methoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol 

Downstream Products

• 342901-71-7 (E)-3-[(2R,4S,5R)-4-((R)-1-Benzyloxy-3-oxo-propyl)-2-phenyl-[1,3]dioxan-5-yloxy]-acrylic acid methyl ester 
• 342902-03-8 C₇₅H₁₀₂O₁₃Si 
• 342902-02-7 C₇₅H₁₀₀O₁₂Si 
• 342902-05-0 C₇₁H₉₀O₁₂S 
• 669005-56-5 {(2R,3S,4R,6R,7S)-4,6-Bis-benzyloxy-7-(2-benzyloxy-ethyl)-2-[(2R,4aR,6S,7R,9S,10aS)-7-(4-methoxy-benzyloxy)-9-methyl-2-phenyl-octahydro-1,3,5-trioxa-benzocycloocten-6-ylmethyl]-oxepan-3-yloxy}-tert-butyl-dimethyl-silane 
• 669005-59-8 (2R,3S,4R,6R,7S)-4,6-Bis-benzyloxy-7-(2-benzyloxy-ethyl)-2-[(2R,4aR,6S,7R,9S,10aS)-7-(4-methoxy-benzyloxy)-9-methyl-2-phenyl-octahydro-1,3,5-trioxa-benzocycloocten-6-ylmethyl]-oxepan-3-ol 
• 669005-71-4 (2R,4R,6R,7S)-4,6-Bis-benzyloxy-7-(2-benzyloxy-ethyl)-2-[(2R,4aR,6S,7R,9S,10aS)-7-(4-methoxy-benzyloxy)-9-methyl-2-phenyl-octahydro-1,3,5-trioxa-benzocycloocten-6-ylmethyl]-oxepan-3-one 
• 342901-85-3 (2R,4aR,6S,7R,9S,10aS)-6-[(2R,3S,4R,6R,7S)-4,6-Bis-benzyloxy-7-(2-benzyloxy-ethyl)-3-(tert-butyl-dimethyl-silanyloxy)-oxepan-2-ylmethyl]-9-methyl-2-phenyl-octahydro-1,3,5-trioxa-benzocycloocten-7-ol 
• 342902-07-2 3,5-bis-benzyloxy-2-(2-benzyloxy-ethyl)-10-(tert-butyl-dimethyl-silanyloxy)-11-(tert-butyl-dimethyl-silanyloxymethyl)-5a,8-dimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cyclooctene 
• 680204-11-9 Acetic acid (2S,3R,5R,5aR,6aR,8R,10S,11R,12aS,13aR)-11-acetoxymethyl-3,5-bis-benzyloxy-2-(2-benzyloxy-ethyl)-5a-ethanesulfonyl-8-methyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-10-yl ester 
• 342902-08-3 [(2S,3R,5R,5aS,6aR,8S,10S,11R,12aS,13aR)-3,5-Bis-benzyloxy-2-(2-benzyloxy-ethyl)-10-(tert-butyl-dimethyl-silanyloxy)-5a,8-dimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-11-yl]-methanol 
• 669005-93-0 [(2S,3R,5R,5aS,6aR,8S,10S,11S,12aS,13aR)-3,5-Bis-benzyloxy-2-(2-benzyloxy-ethyl)-11-iodomethyl-5a,8-dimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-10-yloxy]-tert-butyl-dimethyl-silane 
• 342901-87-5 C₄₆H₅₄O₉ 
• 342901-90-0 [(2S,3R,5R,5aS,6aR,8S,10S,12aS,13aR)-3,5-Bis-benzyloxy-2-(2-benzyloxy-ethyl)-5a,8-dimethyl-11-methylene-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-10-yloxy]-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

Synthetic studies on ciguatoxin: A highly convergent synthesis of the GHIJKLM ring system based on b-alkyl suzuki coupling

Access to polycyclic polyethers is facilitated by a synthetic strategy involving two-step B-alkyl Suzuki coupling reactions for the stereo-selective construction of the polyether skeleton. Thus, a convergent synthetic route to the heptacyclic GHIJKLM ring system 1 of ciguatoxin, a marine algal toxin implicated in ciguatera fish poisoning, was developed. Bn = benzyl.