669062-21-9Relevant academic research and scientific papers
Alcohol uncaging with fluorescence reporting: Evaluation of o-acetoxyphenyl methyloxazolone precursors
Gagey, Nathalie,Emond, Matthieu,Neveu, Pierre,Benbrahim, Chouaha,Goetz, Bernard,Aujard, Isabelle,Baudin, Jean-Bernard,Jullien, Ludovic
supporting information; experimental part, p. 2341 - 2344 (2009/06/06)
(Chemical Equation Presented) This paper evaluates a series of photolabile protecting groups with built-in fluorescence reporting. They rely on readily available o-acetoxyphenyl methyloxazolones as activated precursors. Alcohol substrates are easily caged. The resulting photoactivable esters exhibit large one- and two-photon uncaging cross sections. The alcohol substrates are quantitatively released in a 1:1 molar ratio with a strongly fluorescent coumarin coproduct that serves as a reporter to quantify substrate delivery.
Synthesis of Diverse Macrocyclic Peptidomimetics Utilizing Ring-Closing Metathesis and Solid-Phase Synthesis
Barrett, Anthony G. M.,Hennessy, Alan J.,Le Vezouet, Ronan,Procopiou, Panayiotis A.,Seale, Peter W.,Stefaniak, Stefan,Upton, Richard J.,White, Andrew J. P.,Williams, David J.
, p. 1028 - 1037 (2007/10/03)
The synthesis of a range of highly functionalized peptidomimetic macrocycles has been accomplished using ring-closing metathesis and enyne tandem cross-metathesis-ring-closing metathesis reactions. This approach gives access to rigidified macrocycles mode
