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Relevant academic research and scientific papers

A colorimetric chemosensor based on new water-soluble PODIPY dye for Hg2+ detection

The phosphorus-containing PODIPY 1 as a chemosensor can detect Hg2+ by a color change from pink to violet red without the use of any instrumentation. PODIPY 1 was selective to Hg2+ with a remarkable absorption change, and addition of

A New Water-Soluble Phosphorus-Dipyrromethene and Phosphorus-Azadipyrromethene Dye: PODIPY/aza-PODIPY

PODIPY and aza-PODIPY have been successfully prepared by the treatment of dipyrromethene and azadipyrromethene with POCl3 in the presence of Et3N. The new PODIPY and aza-PODIPY dyes are found to have photophysical properties. PODIPY

Azido-Substituted BODIPY Dyes for the Production of Fluorescent Carbon Nanotubes

A series of azido-dyes were synthesized through Knoevenagel reactions of an azido-BODIPY with aromatic aldehydes. The nature of the substituents allowed the fine tuning of their spectroscopic properties. The dyes were used to decorate oxidized multiwalled

Synthesis, photophysical properties and solvatochromism of meso-substituted tetramethyl BODIPY dyes

The 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene fluorescent dyes (BODIPYs) were first synthesized almost 50 years ago; however, the exploration of their technological application has only begun in the last 20 years. These dyes possess interesting photophys

Study on Liposomal Encapsulation of New Bodipy Sensitizers for Photodynamic Therapy

We report a series of four efficient photosensitizers (PSs) based on a Bodipy core for photodynamic therapy (PDT). In the absence of hydrophilic functional groups, these PSs have been encapsulated in liposomes and examined for photocytotoxicity against hu

Dipyrrin type rare earth metal complex, preparation method and application

The invention relates to a dipyrrin type rare earth metal complex, a preparation method and application, and belongs to the technical field of catalysts. The dipyrrin type rare earth metal complex hashigher catalysis activity and selectivity, and fluoresc

Water-soluble PnO2 - PODIPY/PnO2 - azaPODIPY fluorescent dye and its preparation method

The invention relates to a dye and a preparation method thereof. The fluorescent dye is a series of novel dye which takes PnO2-PODIPY/PnO2-azaPODIPY developed from dipyrrin/aza-dipyrromethene complexing PnO2 (Pn-P, As, Sb, Bi) as a parent nucleus, and the

Intracellular Distribution of Fluorescent Copper and Zinc Bis(thiosemicarbazonato) Complexes Measured with Fluorescence Lifetime Spectroscopy

The intracellular distribution of fluorescently labeled copper and zinc bis(thiosemicarbazonato) complexes was investigated in M17 neuroblastoma cells and primary cortical neurons with a view to providing insights into the neuroprotective activity of a copper bis(thiosemicarbazonato) complex known as CuII(atsm). Time-resolved fluorescence measurements allowed the identification of the CuII and ZnII complexes as well as the free ligand inside the cells by virtue of the distinct fluorescence lifetime of each species. Confocal fluorescent microscopy of cells treated with the fluorescent copper(II)bis(thiosemicarbazonato) complex revealed significant fluorescence associated with cytoplasmic puncta that were identified to be lysosomes in primary cortical neurons and both lipid droplets and lysosomes in M17 neuroblastoma cells. Fluorescence lifetime imaging microscopy confirmed that the fluorescence signal emanating from the lipid droplets could be attributed to the copper(II) complex but also that some degree of loss of the metal ion led to diffuse cytosolic fluorescence that could be attributed to the metal-free ligand. The accumulation of the copper(II) complex in lipid droplets could be relevant to the neuroprotective activity of CuII(atsm) in models of amyotrophic lateral sclerosis and Parkinson's disease.

A design strategy for small molecule-based targeted MRI contrast agents: Their application for detection of atherosclerotic plaques

Gadolinium(III) ion (Gd3+) complexes are widely used as contrast agents in magnetic resonance imaging (MRI), and many attempts have been made to couple them to sensor moieties in order to visualize biological phenomena of interest inside the bo

Light-driven Au(iii)-promoted cleavage of triazole-bearing amine derivatives and its application in the detection of ionic gold

Light-driven Au(iii)-promoted oxidative cleavage of triazole-bearing amine derivatives is utilized for the detection of ionic gold in aqueous media. A bistriazole-bearing boron dipyrromethane (1BODIPY) exhibited selective and sensitive fluoresc