669074-89-9 Usage
Uses
Used in Organic Chemistry Research:
4-(Quinoline-3-carbonyl)-piperidine-1-carboxylic acid tert-butyl ester is used as a research compound in organic chemistry for studying its chemical properties and reactions. Its unique structure allows chemists to explore new synthetic pathways and mechanisms.
Used in Drug Discovery:
In the pharmaceutical industry, 4-(Quinoline-3-carbonyl)-piperidine-1-carboxylic acid tert-butyl ester is used as a lead compound in drug discovery. Its structural features may offer potential therapeutic benefits, and researchers are investigating its interactions with biological targets to identify possible applications in medicine.
Used in Medicinal Chemistry:
4-(Quinoline-3-carbonyl)-piperidine-1-carboxylic acid tert-butyl ester is utilized in medicinal chemistry as a template for the design and synthesis of new pharmaceutical agents. Its structural elements can be modified to create derivatives with improved pharmacological properties, enhancing their potential as therapeutic agents.
Used in Chemical Synthesis:
4-(QUINOLINE-3-CARBONYL)-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER is also used in chemical synthesis as an intermediate or building block for the preparation of more complex organic molecules. Its reactivity and functional groups make it a versatile component in the synthesis of various target compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 669074-89-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,6,9,0,7 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 669074-89:
(8*6)+(7*6)+(6*9)+(5*0)+(4*7)+(3*4)+(2*8)+(1*9)=209
209 % 10 = 9
So 669074-89-9 is a valid CAS Registry Number.
669074-89-9Relevant academic research and scientific papers
1,2,3,4-Tetrahydroquinoline-containing αVβ 3 integrin antagonists with enhanced oral bioavailability
Ghosh, Shyamali,Santulli, Rosemary J.,Kinney, William A.,DeCorte, Bart L.,Liu, Li,Lewis, Joan M.,Proost, Jef C.,Leo, Gregory C.,Masucci, John,Hageman, William E.,Thompson, Andrew S.,Chen, Ian,Kawahama, Reiko,Tuman, Robert W.,Galemmo Jr., Robert A.,Johnson, Dana L.,Damiano, Bruce P.,Maryanoff, Bruce E.
, p. 5937 - 5941 (2007/10/03)
Selective reduction of the quinoline yielded potent α vβ53 antagonists with improved oral bioavailability relative to the corresponding quinoline derivatives. Reduction of the quinoline ring in an αvβ3 antagonist yielded a 1,2,3,4-tetrahydro derivative as two diastereomers, the four isomers of which were separated by sequential chiral HPLC. Two isomers had significant αVβ3 antagonist activity with improved oral bioavailability, relative to the corresponding quinoline derivative.
PIPERIDINYL COMPOUNDS THAT SELECTIVELY BIND INTEGRINS
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Page 87, (2010/11/30)
The invention is directed to piperidinyl compounds of formula (I) and (II) that selectively bind integrin receptors and methods for treating an integrin mediated disorder, wherein W, R2, Z and q are described in the application.
