66934-18-7

Usage

Uses

Used in Pharmaceutical Industry:
Flunoxaprofen is used as an anti-inflammatory agent for the treatment of rheumatoid arthritis, myositis, synovitis, and osteoarthritis. Its lipoxygenase inhibition mechanism allows for effective control of inflammation with reduced risk of gastric disturbances compared to other NSAIDs.
Used in Inflammatory Conditions Treatment:
Flunoxaprofen is used as a therapeutic agent for managing inflammatory conditions, such as rheumatoid arthritis, myositis, synovitis, and osteoarthritis. Its ability to inhibit lipoxygenase helps in reducing inflammation and providing relief from pain and swelling associated with these conditions.

Originator

Ravizza (Italy)

InChI:InChI=1/C16H12FNO3/c1-9(16(19)20)11-4-7-14-13(8-11)18-15(21-14)10-2-5-12(17)6-3-10/h2-9H,1H3,(H,19,20)/t9-/m0/s1

Upstream product

• 51234-43-6 3-amino-4-hydroxyphenyl-2-methylacetic acid 
• 103919-80-8 2(4-fluorophenyl)5-benzoxazole acrylic acid 
• 28694-90-8 2-(4-aminophenyl)-propionitrile 
• 51234-22-1 3-nitro-4-hydroxyphenyl-α-methyl-acetonitrile 
• 21850-61-3 2-(4-hydroxyphenyl)propanenitrile 
• 51234-23-2 2-(3-amino-4-hydroxyphenyl)-propionitrile 
• 403-43-0 4-fluorobenzoyl chloride 

Relevant academic research and scientific papers

Process for preparing 2(4-fluorophenyl)alpha-methyl-5-benzoxazole acetic acid

A process for preparing 2(4-fluorophenyl)α-methyl-5-benzoxazole acetic acid starting from 4-hydroxy-3-amino-phenylacetic acid, which is firstly reacted with 4-fluorobenzoyl chloride, and the product obtained is reacted with phosphoric acid; the 2(4-fluoro

Process for preparing benzoxazolyl propionic acid derivatives

The application describes a process for preparing 2-phenyl derivatives of benzoxazolyl propionic acid of formula STR1 in which X is H, Cl, Br, F, or a linear or branched alkyl or 1 to 6 carbon atoms. The process starts from 3-nitro-4-hydroxyphenyl-α-methy

Benzoxazole derivatives in treating inflammation, pain and fever

The invention provides novel 5- and 6-benzoxazolyl alkanoic acids, optionally substituted in the 2-position, and derivatives thereof which possess anti-inflammatory, anti-pyretic and analgesic activity. Also provided is a process for preparing such compounds by cyclising an appropriately substituted o-aminophenol and, if necessary, converting the resultant benzoxazole to the desired compound.

Anti-inflammatory 1,2-benzisoxazole derivatives

3-Phenyl substituted 1,2-benzisoxazole acetic and propionic acid derivatives with anti-inflammatory activity.