66937-99-3

Basic information

• Product Name: MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE
• Synonyms: MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE;Morpholine-3-carboxylic acid HCl;3-Morpholinecarboxylic Acid Hydrochloride;(RS)-Morpholine-3-carboxylic acid HCl;3-Morpholinecarboxylicacidhydrochloride(1:1)
• CAS NO: 66937-99-3
• Molecular Formula: C5H10ClNO3
• Molecular Weight: 167.5908
• Mol File: 66937-99-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE(66937-99-3)
• EPA Substance Registry System: MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE(66937-99-3)

Safety Data

• Hazardous Substances Data: 66937-99-3(Hazardous Substances Data)

Usage

General Description

Morpholine-3-carboxylic acid hydrochloride is a chemical compound that is commonly used as a corrosion inhibitor and as a building block in the synthesis of pharmaceuticals and other organic compounds. It is a crystalline solid with a white to off-white color, and it is soluble in water. MORPHOLINE-3-CARBOXYLIC ACID HYDROCHLORIDE is particularly known for its ability to inhibit the corrosion of iron and steel in water-based systems, making it a valuable additive in industrial processes such as water treatment and metal manufacturing. Additionally, its molecular structure makes it a versatile starting material for the synthesis of various pharmaceuticals and other complex organic molecules. Overall, morpholine-3-carboxylic acid hydrochloride is an important chemical with a wide range of industrial and pharmaceutical applications.

InChI:InChI=1/C5H9NO3.ClH/c7-5(8)4-3-9-2-1-6-4;/h4,6H,1-3H2,(H,7,8);1H

Upstream product

• 518047-40-0 tert-butyl 3-cyanomorpholine-4-carboxylate 
• 97039-63-9 morpholine-3-carbonitrile 

Downstream Products

• 126264-49-1 methyl 3-morpholine-carboxylate 
• 212650-43-6 4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid 
• 550346-46-8 4-nitrosomorpholine-3-carboxylic acid 

Relevant articles and documents

Preparation method for morpholine-3-carboxylic acid

The invention provides a preparation method for morpholine-3-carboxylic acid. The preparation method comprises the following steps: taking (2-Hydroxyethyl)carbamic acid tert-butyl ester and 2-chloroacrylonitrile as raw materials, performing Michael addition reaction, performing deprotection reaction, performing ring-closure reaction, and performing hydrolysis reaction to obtain the morpholine-3-carboxylic acid. The preparation method for the morpholine-3-carboxylic acid provided by the invention is used for preparing morpholine-3-carboxylic acid through Michael addition reaction, the deprotection reaction, ring-closure reaction and hydrolysis reaction; the whole preparation process is simple, is fewer in steps, adopts cheap and easily available raw materials, is free of stimulus and easilyallergic substances, and avoids generating highly toxic products and side products; and the yield of reaction at each step can be 80% or higher, the total yield is high, large-scale production is facilitated, economic benefits are improved, and the market value is good.

Synthesis of 3-oxadiazolyl/triazolyl morpholines: Novel scaffolds for drug discovery

Synthesis of isomeric 3-oxadiazolyl/triazolyl morpholines was performed based on a common intermediate on the gram scale. The target compounds were designed as novel scaffolds for the medicinal chemistry. The key reaction was an electrochemical CH-oxidati

N2 -arylsulfonyl-l-argininamides and the pharmaceutically acceptable salts thereof

N2 -arylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals.