66938-30-5

Usage

Uses

Used in Pharmaceutical Synthesis:
(2,4-dichlorophenyl)(4-methoxyphenyl)methanone is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs.
Used in Agrochemical Production:
(2,4-dichlorophenyl)(4-methoxyphenyl)methanone also serves as an intermediate in the production of agrochemicals, contributing to the development of pesticides and other agricultural products to improve crop yields and protect plants from pests.
Used in Biological Research:
(2,4-dichlorophenyl)(4-methoxyphenyl)methanone has been studied for its potential biological activities, such as anti-inflammatory and antifungal properties. Its application in research aids in understanding its therapeutic potential and possible integration into treatments.
The specific applications and uses of (2,4-dichlorophenyl)(4-methoxyphenyl)methanone may vary depending on the context and the particular chemical and biological properties of the compound, making it a versatile intermediate in both pharmaceutical and agrochemical industries.

Upstream product

• 29334-25-6 (2,4-dichloro-phenyl)-(4-methoxy-phenyl)-methanol 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 874-42-0 2,4-dichlorobenzaldeyhde 
• 50-84-0 2,4 dichlorobenzoic acid 
• 100-66-3 methoxybenzene 
• 89-75-8 2,4-dichlorobenzoyl chloride 

Downstream Products

• 66938-47-4 (2,4-Dichloro-phenyl)-(4-methoxy-3-nitro-phenyl)-methanone 
• 29334-25-6 (2,4-dichloro-phenyl)-(4-methoxy-phenyl)-methanol 
• 1312211-09-8 C₁₇H₁₆Cl₂O₂ 
• 1312210-90-4 C₁₇H₁₄Cl₂O₂ 
• 66938-69-0 (4-Amino-3-nitro-phenyl)-(2,4-dichloro-phenyl)-methanone 
• 66939-75-1 3,4-Diamino-2',4'-dichlor-benzophenon 

Relevant academic research and scientific papers

Dirhodium-Catalyzed Enantioselective B?H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

The scarcity of reliable methods for synthesizing chiral gem-diarylmethine borons limits their applications. Herein, we report a method for highly enantioselective dirhodium-catalyzed B?H bond insertion reactions with diaryl diazomethanes as carbene precursors. These reactions afforded chiral gem-diarylmethine borane compounds in high yield (up to 99 % yield), high activity (turnover numbers up to 14 300), high enantioselectivity (up to 99 % ee) and showed unprecedented broad functional group tolerance. The borane compounds synthesized by this method could be efficiently transformed into diaryl methanol, diaryl methyl amine, and triaryl methane derivatives with good stereospecificity. Mechanistic studies suggested that the borane adduct coordinated to the rhodium catalyst and thus interfered with decomposition of the diazomethane, and that insertion of a rhodium carbene (generated from the diaryl diazomethane) into the B?H bond was most likely the rate-determining step.

Polymer-supported (2,6-dichloro-4-alkoxyphenyl)(2,4-dichlorophenyl) methanol: A new linker for solid-phase organic synthesis

(Chemical Equation Presented) An acid and base stable hydroxytetrachlorodiphenylmethyl (HTPM) linker is developed for polymer-supported organic synthesis. The linkers reported here are utilized for loading carboxylic acids, amines, alcohols, and phenols, and are stable to Bronsted and Lewis acids, Bronsted bases, and a wide variety of nucleophiles. However, the HTPM linkers can conveniently be cleaved by the solvolytic displacement reactions with 20% TFA.

Acid- and base-stable esters: A new protecting group for carboxylic acids

An acid- and base-stable protecting group for carboxylic acids is described. The esters of (2,6-dichloro-4-methoxyphenyl)(2,4-dichlorophenyl) methanol are stable to Bransted and Lewis acids, Bronsted bases, and a wide variety of nucleophiles; however, the esters can be conveniently deprotected by a solvolytic displacement reaction with 20% trifluoroacetic acid. Georg Thieme Verlag Stuttgart.

Synthesis and structure-activity relationships of benzophenone hydrazone derivatives with insecticidal activity

A broad range of benzophenone hydrazone derivatives was prepared and tested against selected chewing insect pests, allowing the analysis of structure-activity relationships. Good activity was found only when the aromatic rings were substituted at the 4-positions with an halogen atom and a triflate or perhaloalkoxy group. In contrast, a number of substituents on the hydrazone part led to active compounds, the best results being achieved with acyl-type substituents. The excellent laboratory and greenhouse activity of the best representatives was confirmed in semi-field trials against Spodoptera littoralis. ° 2001 Society of Chemical Industry.

Envirocat EPIC(R) as a novel catalyst for acylation of anisole using benzoic acids

Friedel-Crafts acylation of anisole has been carried out using Envirocat EPIC(R) as a novel heterogenous catalyst and benzoic acids under reflux condition. This method is suitable for regioselective acylation of activated aromatics with benzoic acids having electron-donating substituents.

Synthesis and anthelminthic acitivity of alkyl-(5-acyl-1-benzimidazol-2-yl) carbamates

A series of alkyl-(5-acyl-l-H-benzimidazol-2-yl)-carbamates were prepared and screened for anthelminthic activity. Some of them were found to be fully active at low, atoxic oral dose levels against gastro-intestinal nematodes. The activity against Syphacia muris and Strongyloides ratta is indicated. From these studies methyl (5-benzoyl-1-H-benzimidazol-2-yl) carbamate (mebendazole) and methyl [5-(4-fluorobenzoyl)-1-H-benzimidazol-2-yl]carbamate (flubendazole) were selected for detailed investigation.