66938-32-7

Basic information

• Product Name: Methanone, (3,4-dichlorophenyl)(4-methoxyphenyl)-
• CAS NO: 66938-32-7
• Molecular Formula: C14H10Cl2O2
• Molecular Weight: 281.138
• Mol File: 66938-32-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methanone, (3,4-dichlorophenyl)(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (3,4-dichlorophenyl)(4-methoxyphenyl)-(66938-32-7)
• EPA Substance Registry System: Methanone, (3,4-dichlorophenyl)(4-methoxyphenyl)-(66938-32-7)

Safety Data

• Hazardous Substances Data: 66938-32-7(Hazardous Substances Data)

Upstream product

• 6287-38-3 3,4-dichlorobenzaldehyde 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 3024-72-4 3,4-dichlorobenzoyl chloride 
• 100-66-3 methoxybenzene 

Downstream Products

• 66938-71-4 (4-Amino-3-nitro-phenyl)-(3,4-dichloro-phenyl)-methanone 
• 812684-96-1 2-(3,4-dichloro-phenyl)-2-(4-methoxy-phenyl)-[1,3]dioxolane 
• 60013-02-7 3,4-dichlorophenyl 4-hydroxyphenyl ketone 
• 66938-49-6 (3,4-Dichloro-phenyl)-(4-methoxy-3-nitro-phenyl)-methanone 

Relevant articles and documents

Dirhodium-Catalyzed Enantioselective B?H Bond Insertion of gem-Diaryl Carbenes: Efficient Access to gem-Diarylmethine Boranes

The scarcity of reliable methods for synthesizing chiral gem-diarylmethine borons limits their applications. Herein, we report a method for highly enantioselective dirhodium-catalyzed B?H bond insertion reactions with diaryl diazomethanes as carbene precursors. These reactions afforded chiral gem-diarylmethine borane compounds in high yield (up to 99 % yield), high activity (turnover numbers up to 14 300), high enantioselectivity (up to 99 % ee) and showed unprecedented broad functional group tolerance. The borane compounds synthesized by this method could be efficiently transformed into diaryl methanol, diaryl methyl amine, and triaryl methane derivatives with good stereospecificity. Mechanistic studies suggested that the borane adduct coordinated to the rhodium catalyst and thus interfered with decomposition of the diazomethane, and that insertion of a rhodium carbene (generated from the diaryl diazomethane) into the B?H bond was most likely the rate-determining step.

Synthesis and structure-activity relationships of benzophenone hydrazone derivatives with insecticidal activity

A broad range of benzophenone hydrazone derivatives was prepared and tested against selected chewing insect pests, allowing the analysis of structure-activity relationships. Good activity was found only when the aromatic rings were substituted at the 4-positions with an halogen atom and a triflate or perhaloalkoxy group. In contrast, a number of substituents on the hydrazone part led to active compounds, the best results being achieved with acyl-type substituents. The excellent laboratory and greenhouse activity of the best representatives was confirmed in semi-field trials against Spodoptera littoralis. ° 2001 Society of Chemical Industry.

Synthesis and anthelminthic acitivity of alkyl-(5-acyl-1-benzimidazol-2-yl) carbamates

A series of alkyl-(5-acyl-l-H-benzimidazol-2-yl)-carbamates were prepared and screened for anthelminthic activity. Some of them were found to be fully active at low, atoxic oral dose levels against gastro-intestinal nematodes. The activity against Syphacia muris and Strongyloides ratta is indicated. From these studies methyl (5-benzoyl-1-H-benzimidazol-2-yl) carbamate (mebendazole) and methyl [5-(4-fluorobenzoyl)-1-H-benzimidazol-2-yl]carbamate (flubendazole) were selected for detailed investigation.