66957-73-1

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 2871-15-0 Phenyl α-D-galactopyranoside 
• 1464-44-4 phenyl-β-D-glucopyranoside 
• 22348-21-6 1-O-phenyl-2,3,4-tri-O-acetyl-β-D-glucopyranose 
• 910892-79-4 phenyl-(O²,O³,O⁴-triacetyl-O⁶-trityl-β-D-glucopyranoside) 
• 13046-84-9 phenyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-glucopyranoside 

Downstream Products

• 66957-65-1 Phenyl-6-azido-6-deoxy-β-D-glucopyranosid 
• 13046-84-9 phenyl 2,3,4-tri-O-acetyl-6-O-p-toluenesulfonyl-β-D-glucopyranoside 
• 566197-60-2 phenyl 6-azido-2,3,4-tri-O-acetyl-6-deoxy-β-D-glucopyranoside 
• 838086-83-2 phenyl 3,6-anhydro-β-D-glucopyranoside 

Relevant academic research and scientific papers

Synthesis of new quaternary ammonium salts - Derivatives of phenyl glucopyranosides

A new series of quaternary ammonium tosylates - derivatives of phenyl β-D-glucopyranoside - has been produced in reactions of phenyl 2,3,4-tri-O-acetyl-6-O-tosyl-β-D-glucopyranoside with triethylamine, trimethylamine, 4-(N,N-dimethylamino)pyridine, 2-meth

Synthesis of new chiral aryl diphosphite ligands derived from pyranoside backbone of monosacharides and their application in copper-catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones

New chiral aryl diphosphite ligands based on the pyranoside backbones of glucose and galactose were prepared. These ligands were tested in the Cu-catalyzed asymmetric conjugate addition of diethyl-zinc to cyclic enones with up to 88% ee. The stereoselecti

Synthesis of novel HIV-1 protease inhibitors based on carbohydrate scaffolds

The synthesis of peptidomimetic inhibitors of HIV-1 protease based on 6-deoxy-6-amino-β-D-glucopyranoside and 6-deoxy-6-amino-β-D-mannopyranoside scaffolds has been achieved. The inhibitors had IC50 values in the micromolar range. The results provide a platform for the development of more potent carbohydrate based inhibitors of HIV-1 and other aspartic proteases.