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5-Hydroxy-3'-methoxyflavone is a naturally occurring flavonoid compound, characterized by its chemical structure that includes a hydroxyl group at the 5th position and a methoxy group at the 3' position on the flavone ring. Flavonoids are a class of polyphenolic compounds found in plants, known for their antioxidant properties and potential health benefits. 5-Hydroxy-3'-methoxyflavone, in particular, has been studied for its potential roles in various biological activities, such as antioxidant, anti-inflammatory, and anticancer effects. It is typically extracted from plant sources and can be found in certain fruits, vegetables, and medicinal plants. The compound's specific biological activities and mechanisms of action are subjects of ongoing research, with the aim of understanding its potential applications in healthcare and medicine.

6697-60-5

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6697-60-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6697-60-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,9 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6697-60:
(6*6)+(5*6)+(4*9)+(3*7)+(2*6)+(1*0)=135
135 % 10 = 5
So 6697-60-5 is a valid CAS Registry Number.

6697-60-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-hydroxy-2-(3-methoxyphenyl)-chromen-4-one

1.2 Other means of identification

Product number -
Other names 5-hydroxy-3'-methoxyflavone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6697-60-5 SDS

6697-60-5Relevant academic research and scientific papers

Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists

Zhang, Guoning,Liu, Shuainan,Tan, Wenjuan,Verma, Ruchi,Chen, Yuan,Sun, Deyang,Huan, Yi,Jiang, Qian,Wang, Xing,Wang, Na,Xu, Yang,Wong, Chiwai,Shen, Zhufang,Deng, Ruitang,Liu, Jinsong,Zhang, Yanqiao,Fang, Weishuo

, p. 303 - 309 (2017/03/01)

Farnesoid X receptor (FXR), a nuclear receptor mainly distributed in liver and intestine, has been regarded as a potential target for the treatment of various metabolic diseases, cancer and infectious diseases related to liver. Starting from two previously identified chalcone-based FXR antagonists, we tried to increase the activity through the design and synthesis of a library containing chalcones, flavones and chromenes, based on substitution manipulation and conformation (ring closure) restriction strategy. Many chalcones and four chromenes were identified as microM potent FXR antagonists, among which chromene 11c significantly decreased the plasma and hepatic triglyceride level in KKay mice.

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