669709-49-3

Usage

Chemical Class

Quinoline derivative

Functional Groups

Chloro group, carboxylic acid group, pyridine ring

Potential Applications

Antimicrobial, antiviral, agrochemical, chemical research and synthesis
Interesting Compound for Study and Development

InChI:InChI=1/C15H9ClN2O2/c16-10-3-4-13-11(6-10)12(15(19)20)7-14(18-13)9-2-1-5-17-8-9/h1-8H,(H,19,20)

Upstream product

• 350-03-8 methyl-3-pyridylketone 
• 17630-76-1 5-chloroindole 2,3-dione 

Relevant academic research and scientific papers

QUINOLINE COMPOUNDS AS MODULATORS OF RAGE ACTIVITY AND USES THEREOF

Quinoline compounds are disclosed that have a formula represented by the following: and wherein Cy, R1, R4a, R4b, and n are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity.

Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues

CYP2C9 is a significant P450 protein responsible for drug metabolism. With the increased use of heterocyclic compounds in drug design, a rapid and efficient predrug screening of these potential type II binding compounds is essential to avoid adverse drug