66977-99-9Relevant articles and documents
Arseniyadis et al.
, p. 54 (1978)
TRIAZOLE DERIVATIVES AS P2Y14 RECEPTOR ANTAGONISTS
-
, (2017/04/11)
Described are compounds, which are antagonists of the P2Y14 receptor, for example, a compound of formula (I) in which ring A, R1,R2, R3, and n are as described herein. Also provided are dendron conjugates comprising the compounds, and methods of using the compounds, including a method of treating a disorder, such as inflammation, diabetes, insulin resistance, hyperglycemia, a lipid disorder, obesity, a condition associated with metabolic syndrome, and asthma, and a method of antagonizing P214 receptor activity in a cell.
Ni-Catalyzed Divergent Cyclization/Carboxylation of Unactivated Primary and Secondary Alkyl Halides with CO2
Wang, Xueqiang,Liu, Yu,Martin, Ruben
supporting information, p. 6476 - 6479 (2015/06/08)
A user-friendly Ni-catalyzed reductive cyclization/carboxylation of unactivated alkyl halides with CO2 is described. The protocol operates under mild conditions with an excellent chemoselectivity profile and a divergent syn/anti selectivity pat