669772-09-2Relevant academic research and scientific papers
Divergent Synthesis of Molecular Winch Prototypes
Gisbert, Yohan,Abid, Seifallah,Kammerer, Claire,Rapenne, Gwéna?l
supporting information, p. 16242 - 16249 (2021/10/16)
We report the synthesis of conceptually new prototypes of molecular winches with the ultimate aim to investigate the work performed by a single ruthenium-based molecular motor anchored on a surface by probing its ability to pull a load upon electrically-driven directional rotation. According to a technomimetic design, the motor was embedded in a winch structure, with a long flexible polyethylene glycol chain terminated by an azide hook to connect a variety of molecular loads. The structure of the motor was first derivatized by means of two sequential cross-coupling reactions involving a penta(4-halogenophenyl)cyclopentadienyl hydrotris(indazolyl)borate ruthenium(II) precursor and the resulting benzylamine derivative was next exploited as key intermediate in the divergent synthesis of a family of nanowinch prototypes. A one-pot method involving sequential peptide coupling and Cu-catalyzed azide-alkyne cycloaddition was developed to yield four loaded nanowinches, with load fragments encompassing triptycene, fullerene and porphyrin moieties.
Technomimetic molecules: Synthesis of ruthenium(II) 1,2,3,4,5-penta(p- bromophenyl)cyclopentadienyl hydrotris(indazolyl)borate, an organometallic molecular turnstile
Carella, Alexandre,Jaud, Joel,Rapenne, Gwenael,Launay, Jean-Pierre
, p. 2434 - 2435 (2007/10/03)
A short route to prepare a ruthenium complex with a pentaphenyl substituted cyclopentadienyl and a hydrotris(indazolyl)borate ligand is described: this complex can be seen as an organometallic molecular turnstile.
