6698-13-1

Basic information

• Product Name: 4-BROMO-1,3-BENZODIOXOLE
• Synonyms: 4-BROMO-1,3-BENZODIOXOLE;4-Bromo-Benzo[1,3]Dioxole;3-Bromo-1,2-(methylenedioxy)benzene;4-broMobenzo[d][1,3]dioxole;4-broMo-2H-1,3-benzodioxole;1-Bromo-2,3-(methylenedioxy)benzene;1,3-Benzodioxole,4-broMo-
• CAS NO: 6698-13-1
• Molecular Formula: C₇H₅BrO₂
• Molecular Weight: 201.02
• Mol File: 6698-13-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 82 °C
• Flash Point: 109.652°C
• Appearance: /
• Density: 1.721g/cm³
• Vapor Pressure: 0.066mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-BROMO-1,3-BENZODIOXOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1,3-BENZODIOXOLE(6698-13-1)
• EPA Substance Registry System: 4-BROMO-1,3-BENZODIOXOLE(6698-13-1)

Safety Data

• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 6698-13-1(Hazardous Substances Data)

Usage

General Description

4-BROMO-1,3-BENZODIOXOLE is a chemical compound with the molecular formula C8H7BrO2. It is a brominated derivative of benzodioxole and is used in the synthesis of pharmaceuticals and organic compounds. This chemical is a white solid with a high melting point and is insoluble in water but soluble in organic solvents. It is primarily used as an intermediate in the production of various substances, including pharmaceuticals, fragrances, and agrochemicals. 4-BROMO-1,3-BENZODIOXOLE is also used in research and development for the synthesis of novel compounds and has potential applications in the pharmaceutical and chemical industries.

InChI:InChI=1/C7H5BrO2/c8-5-2-1-3-6-7(5)10-4-9-6/h1-3H,4H2

Upstream product

• 75-11-6 diiodomethane 
• 14381-51-2 3-bromo-1,2-dihydroxybenzene 
• 74-95-3 1,1-dibromomethane 

Downstream Products

• 7228-40-2 1-(benzo[d][1,3]dioxol-4-yl)ethanol 
• 5354-08-5 5-(methylthio)benzo[d][1,3]dioxole 
• 1395921-61-5 trans-N-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-carbamic acid methyl ester 
• 1395921-44-4 trans-N-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-acetamide 
• 1395922-25-4 trans-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-carbamic acid tert-butyl ester 
• 1395922-19-6 N-trans-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-3-(4-chloro-phenyl)-urea 
• 1395922-18-5 N-trans-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-2-fluoro-acetamide 
• 1395922-15-2 trans-N-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-2,2,2-trifluoro-acetamide 
• 1395922-11-8 trans-N-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-methanesulfonamide 
• 1395922-20-9 Trans-N-{4-[2-(4-benzo[1,3]dioxol-4-yl-piperidin-1-yl)-ethyl]-cyclohexyl}-N,N-dimethyl-sulfamide 
• 105684-23-9 1-(benzo[d][1,3]dioxol-4-yl)piperazine hydrochloride 

Relevant articles and documents

FUSED RING PYRIMIDINE COMPOUND, INTERMEDIATE, AND PREPARATION METHOD, COMPOSITION AND USE THEREOF

Disclosed area fused ring pyrimidine compound, and an intermediate, a preparation method, a composition and a use thereof. The fused ring pyrimidine compound is a compound as shown in formula I, a tautomer, an enantiomer, a diastereoisomer, a pharmaceutically acceptable salt, a metabolite, a metabolic precursor or a prodrug thereof, wherein the above-mentioned compound is used for the preparation of a medicine for preventing, remitting or treating one or more of immune system diseases, autoimmune diseases, cell proliferative diseases, allergic disorders and cardiovascular diseases, and the compound has a strong inhibitory effect on the Janues kinase, FGFR kinase, FLT3 kinase and Src family kinase.

Synthesis of 5,6-methylenedioxy-1-tetralone. An aryl Grignard approach from guaiacol

A convenient synthesis of 5,6-methylenedioxy-1-tetralone (1) is described. The main features of this synthesis are the formation of 6 via a Grignard reaction using succinic anhydride followed by selective reduction and Friedel-Crafts cyclization to generate the desired tetralone 1.

Substituted sulfonamides 1,3-benzodioxole

Novel N-[pyrimidin-2-yl]- and [triazin-2-yl]aminocarbonyl-1,3-benzodioxolesulfonamides and 1,4-benzodioxansulfonamides are useful as plant growth regulants and in particular as herbicides.