6698-26-6 Usage
Uses
Used in Pharmaceutical Research:
2',5'-DIDEOXYADENOSINE is used as a research tool for elucidating the mechanism of action of certain compounds, such as diligustilide (DLG). Its unique structure allows for the investigation of molecular interactions and signaling pathways, contributing to a better understanding of drug action and potential therapeutic targets.
Used in Enzyme Inhibition:
2',5'-DIDEOXYADENOSINE is used as an inhibitor of adenylate cyclase (AC), an enzyme that plays a crucial role in cellular signaling by catalyzing the conversion of ATP to cyclic AMP (cAMP). By inhibiting AC, 2',5'-DIDEOXYADENOSINE can modulate cellular processes and potentially be utilized in the development of therapeutic agents targeting specific diseases or conditions.
Biochem/physiol Actions
Cell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.
Check Digit Verification of cas no
The CAS Registry Mumber 6698-26-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,6,9 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6698-26:
(6*6)+(5*6)+(4*9)+(3*8)+(2*2)+(1*6)=136
136 % 10 = 6
So 6698-26-6 is a valid CAS Registry Number.
6698-26-6Relevant academic research and scientific papers
Synthesis of 2',5'-dideoxy-adenosine-3'-monophosphate derivatives as allosteric inhibitors of adenylyl cyclase
Desaubry,Shoshani,Johnson
, p. 1453 - 1460 (2007/10/03)
The synthesis of a fluorescent and a lipophilic conjugate of 2',5'- dideoxy-3'AMP, an allosteric inhibitor of adenylyl cyclase, has been devised.
