670-35-9Relevant articles and documents
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Yamada
, p. 1329,1333 (1962)
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Synthesis of 4-dialkylamino-and 3-halo-6-methyl-4-methoxy-2-pyranones and their 5,6-dihydro derivatives
Lokot,Pashkovskii,Lakhvich
, p. 1350 - 1354 (2007/10/03)
A new procedure has been developed for preparation of 4-dialkylamino-6-methyl-2-pyranones and their 5,6-dihydro analogs by reaction of cyclic amines with 4-chloro- and 4-methoxy-2-pyranones. Chlorine and bromine can be introduced into position 3 of the 2-pyranone and 5,6-dihydro-2-pyranone rings via reaction of 4-methoxy derivatives with N-halosuccinimides. In the presence of two equivalents of N-halosuccinimide 3-halo-4-methoxy-6-methyl-5,6-dihydro-2-pyranone is converted into 3-halo-4-methoxy-6-methyl-2-pyranone.
Functionalization at C-5 and at the C-6 Methyl Group of 4-Methoxy-6-methyl-2-pyrone
Bacardit, R.,Moreno-Manas, M.,Pleixats, R.
, p. 157 - 160 (2007/10/02)
A new entry to C-5 substituted 4-hydroxy-6-methyl-2-pyrones has been achieved.The best conditions to prepare the monobromo and the dibromo derivatives at C-3 and the C-6 methyl group of the title pyrone have been defined.The synthetic applicability of the phosphonium salts at CH3-C-6 of both 4-methoxy-6-methyl-2-pyrone, 5, and dehydroacetic acid, 2, has also been evaluated.