67005-21-4 Usage
Description
4-(3-Bromophenyl)-6-phenylpyrimidin-2-amine, commonly referred to as "BPPA", is a chemical compound characterized by a pyrimidine core structure, with a bromophenyl group at the 4-position and a phenyl group at the 6-position. This unique molecular arrangement endows BPPA with potential therapeutic applications, particularly as a kinase inhibitor. Its anti-cancer and anti-inflammatory properties have been the subject of research, and it holds promise for further exploration in drug development and medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
BPPA is utilized as a kinase inhibitor for its potential anti-cancer properties. Its ability to target specific kinases involved in cell proliferation and survival pathways makes it a candidate for the development of targeted cancer therapies.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, BPPA serves as a valuable compound for studying the structure-activity relationships of kinase inhibitors. Its unique structure and biological activity provide insights into the design of more potent and selective therapeutic agents.
Used in Anti-inflammatory Applications:
BPPA is also considered for its potential anti-inflammatory effects. Given the role of kinases in inflammatory pathways, BPPA may be developed as a treatment for inflammatory disorders by modulating these pathways.
Used in Drug Development:
The exploration of BPPA's potential in drug development is ongoing, with its unique structure and biological activity making it a promising candidate for the creation of new therapeutic agents targeting various diseases beyond cancer and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 67005-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,0,0 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67005-21:
(7*6)+(6*7)+(5*0)+(4*0)+(3*5)+(2*2)+(1*1)=104
104 % 10 = 4
So 67005-21-4 is a valid CAS Registry Number.
67005-21-4Relevant articles and documents
Iron-Catalyzed Alkyne-Based Multicomponent Synthesis of Pyrimidines under Air
Chakraborty, Gargi,Guin, Amit Kumar,Mondal, Rakesh,Paul, Nanda D.,Sarkar, Susmita
, p. 13186 - 13197 (2021/10/01)
An iron-catalyzed sustainable, economically affordable, and eco-friendly synthetic protocol for the construction of various trisubstituted pyrimidines is described. A wide range of trisubstituted pyrimidines were prepared using a well-defined, easy to prepare, bench-stable, and phosphine-free iron catalyst featuring a redox-noninnocent tridentate arylazo pincer under comparatively mild aerobic conditions via dehydrogenative functionalization of alcohols with alkynes and amidines.
