67005-21-4 Usage
Uses
Used in Pharmaceutical Industry:
BPPA is utilized as a kinase inhibitor for its potential anti-cancer properties. Its ability to target specific kinases involved in cell proliferation and survival pathways makes it a candidate for the development of targeted cancer therapies.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, BPPA serves as a valuable compound for studying the structure-activity relationships of kinase inhibitors. Its unique structure and biological activity provide insights into the design of more potent and selective therapeutic agents.
Used in Anti-inflammatory Applications:
BPPA is also considered for its potential anti-inflammatory effects. Given the role of kinases in inflammatory pathways, BPPA may be developed as a treatment for inflammatory disorders by modulating these pathways.
Used in Drug Development:
The exploration of BPPA's potential in drug development is ongoing, with its unique structure and biological activity making it a promising candidate for the creation of new therapeutic agents targeting various diseases beyond cancer and inflammation.
Check Digit Verification of cas no
The CAS Registry Mumber 67005-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,0,0 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 67005-21:
(7*6)+(6*7)+(5*0)+(4*0)+(3*5)+(2*2)+(1*1)=104
104 % 10 = 4
So 67005-21-4 is a valid CAS Registry Number.
67005-21-4Relevant academic research and scientific papers
Iron-Catalyzed Alkyne-Based Multicomponent Synthesis of Pyrimidines under Air
Chakraborty, Gargi,Guin, Amit Kumar,Mondal, Rakesh,Paul, Nanda D.,Sarkar, Susmita
, p. 13186 - 13197 (2021/10/01)
An iron-catalyzed sustainable, economically affordable, and eco-friendly synthetic protocol for the construction of various trisubstituted pyrimidines is described. A wide range of trisubstituted pyrimidines were prepared using a well-defined, easy to prepare, bench-stable, and phosphine-free iron catalyst featuring a redox-noninnocent tridentate arylazo pincer under comparatively mild aerobic conditions via dehydrogenative functionalization of alcohols with alkynes and amidines.
Iron Catalyzed Synthesis of Pyrimidines Under Air
Mondal, Rakesh,Sinha, Suman,Das, Siuli,Chakraborty, Gargi,Paul, Nanda D.
supporting information, p. 594 - 600 (2019/12/15)
Herein we report an iron-catalyzed multicomponent dehydrogenative functionalization of alcohols to pyrimidines under atmospheric conditions. Using a well-defined Fe(II)-complex featuring redox noninnocent 2-phenylazo-(1,10-phenanthroline) ligand, as a cat