670220-85-6Relevant academic research and scientific papers
Synthesis, Modeling, and Anti-Tubulin Activity of a D-Seco Paclitaxel Analogue
Barboni, Luciano,Giarlo, Guido,Ricciutelli, Massimo,Ballini, Roberto,Georg, Gunda I.,VanderVelde, David G.,Himes, Richard H.,Wang, Minmin,Lakdawala, Ami,Snyder, James P.
, p. 461 - 464 (2004)
(Equation presented) We have previously described a model of paclitaxel-microtubule binding that led to the prediction that analogues of paclitaxel lacking any D ring could stabilize microtubules as well as paclitaxel if the substituent present at C4 did
