670241-69-7Relevant academic research and scientific papers
Self-Assembly in a Bipolar Phosphocholine-Water System: The Formation of Nanofibers and Hydrogels
Koehler, Karen,Foerster, Guenter,Hauser, Anton,Dobner, Bodo,Heiser, Ulrich F.,Ziethe, Friederike,Richter, Walter,Steiniger, Frank,Drechsler, Markus,Stettin, Heiko,Blume, Alfred
, p. 245 - 247 (2004)
The bolaamphiphile PC-C32-PC with two phosphocholine headgroups and one long C32 alkyl chain (see the space-filling model, left) forms nanofibrils in aqueous solution at room temperature solely by hydrophobic interactions. The gels that result were studied by electron microscopy (image on the right), differential scanning calorimetry, and FT-IR spectroscopy. At higher temperatures the fibers "melt" and small aggregates form.
General synthesis and aggregation behaviour of a series of single-chain 1,ω-Bis(phosphocholines)
Drescher, Simon,Meister, Annette,Blume, Alfred,Karlsson, Goeran,Almgren, Mats,Dobner, Bodo
, p. 5300 - 5307 (2008/02/11)
The synthesis and physicochemical characterisation of a series of polymethylene-1,ω-bis(phosphocholines) with even-numbered chain lengths between 22 and 32 carbon atoms is described. Two new synthetic strategies for the preparation of long-chain 1,ω-diols as hydrocarbon building blocks are presented. The temperature-dependent self-assembly of the single-chain bolaamphiphiles was investigated by cryo transmission electron microscopy (cryo-TEM), differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FTIR).
