670259-16-2Relevant articles and documents
Identification of 3 H -naphtho[1,2,3- de ]quinoline-2,7-diones as inhibitors of apoptosis signal-regulating kinase 1 (ASK1)
Volynets, Galyna P.,Chekanov, Maksym O.,Synyugin, Anatoliy R.,Golub, Andriy G.,Kukharenko, Oleksandr P.,Bdzhola, Volodymyr G.,Yarmoluk, Sergiy M.
experimental part, p. 2680 - 2686 (2011/06/27)
Apoptosis signal-regulating kinase 1 (ASK1) has recently emerged as an attractive therapeutic target for the treatment of cardiac and neurodegenerative disorders. The selective inhibitors of ASK1 may become important compounds for the development of clini