67045-30-1

Basic information

• Product Name: 2-[(2,4-dimethylphenyl)methyl]phenol
• CAS NO: 67045-30-1
• Molecular Weight: 212.291
• Mol File: 67045-30-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-[(2,4-dimethylphenyl)methyl]phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2,4-dimethylphenyl)methyl]phenol(67045-30-1)
• EPA Substance Registry System: 2-[(2,4-dimethylphenyl)methyl]phenol(67045-30-1)

Safety Data

• Hazardous Substances Data: 67045-30-1(Hazardous Substances Data)

Upstream product

• 90-01-7 salicylic alcohol 
• 108-38-3 m-xylene 
• 90-02-8 salicylaldehyde 
• 16054-72-1 Bis-(2,4-dimethylbenzyl)-ether 
• 108-95-2 phenol 

Relevant articles and documents

Bisulfate Salt-Catalyzed Friedel-Crafts Benzylation of Arenes with Benzylic Alcohols

We report here a method of direct Friedel-Crafts benzylation of arenes with benzylic alcohols using cheap and readily available bisulfate salt as the catalyst in hexafluoroisopropanol. The catalytic system is powerful with a quite diverse group of functionalized arenes and benzylic alcohols. These mild conditions provide a straightforward synthesis of a variety of unsymmetrical diarylmethanes in high yield with good to high regioselectivity. An SN1 mechanism involving activation of the hydroxy group through a hydrogen bond is proposed.