6707-69-3

Basic information

• Product Name: Benzoic acid, 2-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-
• CAS NO: 6707-69-3
• Molecular Formula: C14H17NO5
• Molecular Weight: 279.293
• Mol File: 6707-69-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-(6707-69-3)
• EPA Substance Registry System: Benzoic acid, 2-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]-(6707-69-3)

Safety Data

• Hazardous Substances Data: 6707-69-3(Hazardous Substances Data)

Upstream product

• 61-90-5 L-leucine 
• 88-95-9 Phthaloyl dichloride 
• 85-44-9 phthalic anhydride 
• 244047-66-3 N-(2-carboxybenzoyl)-L-leucine methyl ester 
• 7517-19-3 methyl (L)-leucinate hydrochloride 
• 67-56-1 methanol 
• 2419-38-7 N-phthaloyl-(S)-leucine 
• 22509-74-6 N-ethoxycarbonylphthalimide 
• 2743-40-0 L-leucine ethyl ester hydrochloride 

Downstream Products

• 88-99-3 benzene-1,2-dicarboxylic acid 
• 328-39-2 LEUCINE 
• 61-90-5 L-leucine 
• 2419-38-7 N-phthaloyl-(S)-leucine 

Relevant articles and documents

Reactions of N-(o-carboxybenzoyl)-L-leucine: Intramolecular catalysis of amide hydrolysis and imide formation by two carboxy groups

The intramolecular reactions of N-(o-carboxybenzoyl)-L-leucine (1) were studied in aqueous solution, as a function of the hydrogen ion concentration. Two competing reactions were observed: i) cyclization to form the imide N-phthaloylleucine, and ii) hydrolysis of (1) to phthalic acid and leucine. Individual rate constants for cyclization and hydrolysis were obtained from the overall rate constants and product distributions. Imide formation predominates under highly acidic conditions (H0 0 > -1 to pH 5 range. In the hydrolysis reaction, the neighbouring carboxy group participates nucleophilically and in the pH 3-5 range there is a requirement for participation of the second carboxy group as a general acid. Imide formation also requires participation of two carboxy groups in the pH 2-5 range, and shows a bell-shaped pH-rate constant profile. Possible mechanisms for these reactions are discussed.

1-PYRENYLMETHYL ESTERS, PHOTOLABILE PROTECTING GROUPS FOR CARBOXYLIC ACIDS

1-Diazomethylpyrenes were prepared and reacted with carboxylic acids to give 1-pyrenylmethyl esters.The fluorescent esters were photolysed at 340 nm in methanol to form the starting acids and the corresponding 1-methoxymethylpyrenes in high yields.