671-41-0

Usage

Uses

Used in Pharmaceutical Industry:
5-FLUORO-4-MERCAPTO-2-HYDROXYPYRIMIDINE is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in the treatment of cancer. Its unique chemical structure allows for the development of new drugs that can target specific biological pathways and mechanisms involved in cancer progression.
Used in Agrochemical Industry:
In the agrochemical industry, 5-FLUORO-4-MERCAPTO-2-HYDROXYPYRIMIDINE is utilized as an intermediate in the development of herbicides and pesticides. Its chemical properties enable the creation of effective agents that can control and manage various types of weeds and pests, thereby enhancing crop productivity and protection.
Used in Chemical Production:
5-FLUORO-4-MERCAPTO-2-HYDROXYPYRIMIDINE is employed as a building block in the production of various chemical products due to its diverse chemical and biological properties. Its versatility allows for its incorporation into a wide range of applications, from the synthesis of new compounds to the modification of existing ones, contributing to the advancement of the chemical industry.

InChI:InChI=1/C4H3FN2OS/c5-2-1-6-4(8)7-3(2)9/h1H,(H2,6,7,8,9)

Upstream product

• 51-21-8 5-fluorouracil 
• 7440-44-0 pyrographite 
• 51-21-8 5-fluorouracil 

Downstream Products

• 22462-34-6 4-chloro-5-fluoro-2(1H)-pyrimidone 
• 2022-78-8 5-fluoro-2-pyrimidinone 

Relevant academic research and scientific papers

5-FLUOROPYRIMIDINONE DERIVATIVES

This present disclosure is related to the field of 5-fluoropyrimidinones and their derivatives and to the use of these compounds as fungicides.

Antitumor Properties of 2(1H)-Pyrimidinone Riboside (Zebularine) and Its Fluorinated Analogues

2(1H)-Pyrimidinone riboside (zebularine, 1b) and its 5-fluoro (6b) and 2'-ara-fluoro (7b) analogues have been synthesized and evaluated in vivo as antitumor agents.Zebularine provides increase in life span (ILS) values of ca. 70percent against intraperito

A Rapid and Efficient Synthesis of Sulfur Analogues of Pyrimidine Bases

An improved procedure for thionation of some natural pyrimidine bases with tetraphosphorus decasulfide/sodium hydrogen carbonate is reported.Some substituted uracils and 2-thiouracils were converted into a series of analogues in which the oxygen at position 4 was replaced by sulfur atom.The advantage of this method of thionation over the older procedures is based on the tetraphosphorus decasulfide/sodium hydrogen carbonate mixture giving rise to excellent yields and simplified isolation of the desired pure products.

Antipsychotic 5-fluoro-pyrimidin-2-yl piperazine compound

8-[4-[4-(5-Fluoro-pyrimidin-2-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione and its pharmaceutically acceptable salts demonstrate antipsychotic activity.