67109-87-9

Upstream product

• 3601-36-3 methyl 2,3,6-tri-O-benzoyl-α-D-galactopyranoside 
• 125392-60-1 (2R,3S,4S,5R,6S)-3,4,5-tris(benzyloxy)-2-((benzyloxy)methyl)-6-(pent-4-en-1-yloxy)tetrahydro-2H-pyran 
• 10257-28-0 D-Galactose 
• 98-88-4 benzoyl chloride 
• 132871-95-5 pent-4-enyl O-α-D-galactopyranoside 
• 74801-29-9 phenyl-2,3,4,6-tetra-O-benzyl-1-thio-β-D-galactopyranoside 

Downstream Products

• 887907-59-7 methyl 4-O-(α-D-galactopyranosyl)-2,3,6-tri-O-benzoyl-α-D-galactopyranoside 

Relevant academic research and scientific papers

SYNTHESIS AND USE OF GLYCODENDRIMER REAGENTS

The present invention relates to a chemically modified mutant protein including a cysteine residue substituted for a residue other than cysteine n a precursor protein, the substituted cysteine residue being subsequently modified by reacting the cysteine residue with a glycosylated thiosulfonate. Also a method of producing the chemically modified mutant protein is provided. The present invention also relates to a glycosylated methanethiosulfonate. Another aspect of the present invention is a method of modifying the functional characteristics of a protein including providing a protein and reacting the protein with a glycosylated methanethiosulfonate reagent under conditions effective to produce a glycoprotein with altered functional characteristics as compared to the protein. In addition, the present invention relates to methods of determining the structure-function relationships of chemically modified mutant proteins. The present invention also relates to synthetic methods for producing thio-glycoses, the thio-glycoses so produced, and to methods for producing glycodendrimer reagents.

Glycosidase-catalysed synthesis of glycosides by an improved procedure for reverse hydrolysis: Application to the chemoenzymatic synthesis of galactopyranosyl-(1 → 4)-O-α-galactopyranoside derivatives

β-Galactosidase from Aspergillus oryzae, α-galactosidase from Aspergillus niger, β-mannosidase from Helix pomatia and β-glucosidase from almond were used to synthesise different glycosides by reverse hydrolysis: GlcβO(CH2)6OH 1 was o