67112-59-8 Usage
Description
(3R)-4-amino-3-(4-methylphenyl)butanoic acid hydrochloride is a hydrochloride salt with a molecular formula of C11H16ClNO2. It is a chiral compound featuring an amino group, a carboxylic acid group, and a methylphenyl group attached to a four-carbon backbone. The hydrochloride salt forms the counterion, and its structural features, including chiral centers and an aromatic moiety, may contribute to potential applications in pharmaceutical development and biochemical research.
Uses
Used in Pharmaceutical Development:
(3R)-4-amino-3-(4-methylphenyl)butanoic acid hydrochloride is used as a potential precursor in the synthesis of medications due to its unique structural features, including chiral centers and an aromatic moiety. Its ability to be modified or serve as a building block for other compounds makes it valuable in the development of new drugs.
Used in Biochemical Research:
In biochemical research, (3R)-4-amino-3-(4-methylphenyl)butanoic acid hydrochloride is used as a compound for studying its biological activity and interactions with biological systems. Its structural components may allow it to be utilized in assays and experiments aimed at understanding its effects on biological processes or as a tool to probe specific biochemical pathways.
Used in Chemical Synthesis:
(3R)-4-amino-3-(4-methylphenyl)butanoic acid hydrochloride is used as a synthetic intermediate in the chemical industry for the production of other related compounds. Its versatile structure allows it to be a key component in the synthesis of various organic molecules, potentially leading to new materials or pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 67112-59-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,1 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 67112-59:
(7*6)+(6*7)+(5*1)+(4*1)+(3*2)+(2*5)+(1*9)=118
118 % 10 = 8
So 67112-59-8 is a valid CAS Registry Number.
67112-59-8Relevant articles and documents
Divergent Synthesis of γ-Amino Acid and γ-Lactam Derivatives from meso-Glutaric Anhydrides
Connon, Stephen J.,Craig, Ryan,Smith, Simon N.
supporting information, p. 13378 - 13382 (2020/10/02)
The first divergent synthesis of both γ-amino acid and γ-lactam derivatives from meso-glutaric anhydrides is described. The organocatalytic desymmetrisation with TMSN3 relies on controlled generation of a nucleophilic ammonium azide species mediated by a polystyrene-bound base to promote efficient silylazidation. After Curtius rearrangement of the acyl azide intermediate to access the corresponding isocyanate, hydrolysis/alcoholysis provided uniformly high yields of γ-amino acids and their N-protected counterparts. The same intermediates were shown to undergo an unprecedented decarboxylation–cyclisation cascade in situ to provide synthetically useful yields of γ-lactam derivatives without using any further activating agents. Mechanistic insights invoke the intermediacy of an unconventional γ-N-carboxyanhydride (γ-NCA) in the latter process. Among the examples prepared using this transformation are 8 APIs/molecules of considerable medicinal interest.
Synthesis of Nonracemic Tetrazole GABA Analogs
Reznikov,Ostrovskii,Klimochkin, Yu. N.
, p. 1715 - 1721 (2019/02/14)
Nonracemic 3-substituted 4-(1H-tetrazol-1-yl)butanoic acids, analogs of the neurotropic drugs phenibut, tolibut, and baclofen, were synthesized by a three-component reaction of the R-isomers of the corresponding amino acids, triethyl orthoformate, and sod
