67116-97-6

Basic information

• Product Name: 2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)-
• CAS NO: 67116-97-6
• Molecular Formula: C16H14N2O2
• Molecular Weight: 266.299
• Mol File: 67116-97-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)-(67116-97-6)
• EPA Substance Registry System: 2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)-(67116-97-6)

Safety Data

• Hazardous Substances Data: 67116-97-6(Hazardous Substances Data)

Usage

General Description

2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)- is a chemical compound that belongs to the quinazoline class. It is a white to yellowish crystalline powder that is sparingly soluble in water but soluble in organic solvents. 2,4(1H,3H)-Quinazolinedione, 3-(2,3-dimethylphenyl)- has potential applications in the pharmaceutical industry, specifically in the development of drugs for a variety of medical conditions. Its chemical structure and properties make it a promising candidate for further investigation and research in drug discovery and development.

Upstream product

• 1567-04-0 C₁₇H₁₈N₂O₃ 
• 1591-99-7 1-isocyanato-2,3-dimethylbenzene 
• 87-59-2 2,3-Dimethylaniline 
• 5100-23-2 2-isocyanatobenzoyl chloride 
• 118-48-9 isatoic anhydride 
• 84772-24-7 3-(o,m-Dimethylphenyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydrochinazolin 

Downstream Products

• 869716-01-8 2-chloro-3-(2,3-dimethylphenyl)quinazoline-4(3H)-one 
• 94743-24-5 3-(2,3-Dimethyl-phenyl)-1-[1-(2,2-diphenyl-ethyl)-3,3-dimethyl-2-oxo-butyl]-1H-quinazoline-2,4-dione 
• 94743-23-4 1-[3,3-Dimethyl-2-oxo-1-(3-phenyl-propyl)-butyl]-3-(2,3-dimethyl-phenyl)-1H-quinazoline-2,4-dione 
• 94743-22-3 1-(3,3-Dimethyl-2-oxo-1-phenethyl-butyl)-3-(2,3-dimethyl-phenyl)-1H-quinazoline-2,4-dione 
• 94743-21-2 1-(1-Benzyl-3,3-dimethyl-2-oxo-butyl)-3-(2,3-dimethyl-phenyl)-1H-quinazoline-2,4-dione 
• 94743-20-1 1-(3,3-Dimethyl-2-oxo-1-phenyl-butyl)-3-(2,3-dimethyl-phenyl)-1H-quinazoline-2,4-dione 

Relevant articles and documents

Palladium(0)-catalyzed carbon-Hydrogen bond functionalization for the synthesis of indoloquinazolinones

The indoloquinazolinone ring system has attracted considerable attention as a pharmacophore, because it shows various biological activities. The reported synthetic methods for the compound are simple and direct, but are not effective for the direct synthesis of indoloquinazolinone with a methylene group at the C-6 position. A palladium(0)-catalyzed cyclization of chloroquinazolinone via C-H functionalization was developed for a concise synthesis of indoloquinazolinone derivatives. The presence of a substituent at the C-6 position is important for obtaining the product in good yield. The conformation of the reaction intermediate, in particular the N-C-Pd bond angle, is important for the regioselectivity of the reaction.

On the hydrazinolysis of 3-aryl-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazolines and their derivatives. Synthesis of compounds with aminoguanidine structure. VII

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