67130-14-7

Basic information

• Product Name: 3,4,5,6-TETRAMETHYLBENZENE-1,2-DIAMINE
• Synonyms: 2-Amino-3,4,5,6-tetramethylphenylamine
• CAS NO: 67130-14-7
• Molecular Formula: C₁₀H₁₆N₂
• Molecular Weight: 164.2504
• Mol File: 67130-14-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 139-140 °C(Solv: water (7732-18-5); ethanol (64-17-5))
• Boiling Point: 309.3°C at 760 mmHg
• Flash Point: 166.9°C
• Appearance: /
• Density: 1.032g/cm³
• Vapor Pressure: 0.000645mmHg at 25°C
• Refractive Index: 1.594
• PKA: 5.00±0.10(Predicted)
• CAS DataBase Reference: 3,4,5,6-TETRAMETHYLBENZENE-1,2-DIAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4,5,6-TETRAMETHYLBENZENE-1,2-DIAMINE(67130-14-7)
• EPA Substance Registry System: 3,4,5,6-TETRAMETHYLBENZENE-1,2-DIAMINE(67130-14-7)

Safety Data

• Hazardous Substances Data: 67130-14-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C10H16N2/c1-5-6(2)8(4)10(12)9(11)7(5)3/h11-12H2,1-4H3

Upstream product

• 18801-63-3 3,4,5,6-tetramethyl-1,2-dinitrobenzene 
• 488-23-3 1,2,3,4-Tetramethylbenzene 
• 1887-60-1 5,6-dimethylbenzo-2,1,3-thiadiazole 
• 16219-54-8 4,7-di(chloromethyl)-5,6-dimethylbenzo-2,1,3-thiadiazole 
• 18801-64-4 2,3,4,5-tetramethyl-6-nitro-aniline 
• 64-19-7 acetic acid 

Downstream Products

• 103853-63-0 4,5,6,7-tetramethyl-1,3-dihydro-benzimidazol-2-one 
• 782471-88-9 dimethoxyprehnitene 
• 17483-47-5 tetramethyl-o-quinone 
• 147503-27-3 2,2,2',2'-Tetramethyl-N,N'-(3,4,5,6-tetramethylphen-1,2-ylen)bis 
• 106148-67-8 4,5,6,7-tetramethylbenzimidazole 
• 106148-68-9 2-benzyl-4,5,6,7-tetramethylbenzimidazole hydrochloride 
• 3938-11-2 dihydroxyprehnitene 

Relevant articles and documents

Synthesis and activity of 1H-benzimidazole and 1H-benzotriazole derivatives as inhibitors of Acanthamoeba castellanii

Chloro-, bromo- and methyl- analogues of 1H-benzimidazole and 1H-benzotriazole and their N-alkyl derivatives have been synthesized and tested in vitro against the protozoa Acanthamoeba castellanii. The results indicate that 5,6-dimethyl-1H-benzotriazole (11) and 5,6-dibromo-1H-benzotriazole (14) have higher efficacy than the antiprotozoal agent chlorohexidine.

A NEW SYNTHESIS OF DIAMINOPREHNITOL

The reaction of 4,7-di(chloromethyl)-5,6-dimethylbenzo-2,1,3-thiadiazole with a small excess of tin(II) chloride leads to a high yield of tetramethylbenzo-2,1,3-thiadiazole.With a large excess of tin chloride the thiadiazole ring is cleaved to 1,2,3,4-tet