67139-79-1

Basic information

• Product Name: 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE
• Synonyms: 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE;Nsc293337;6-dichloro-1H-pyrrolo[3;1H-Pyrrolo[3,2-c]pyridine, 4,6-dichloro-;4,6-Dichloro-5-azaindole
• CAS NO: 67139-79-1
• Molecular Formula: C₇H₄Cl₂N₂
• Molecular Weight: 187.02606
• EINECS: 200-258-5
• Product Categories: CHIRAL CHEMICALS;Heterocycle-Pyridine series
• Mol File: 67139-79-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 258 °C(Solv: ethyl acetate (141-78-6))
• Boiling Point: 371.6°C at760mmHg
• Flash Point: 210.2°C
• Appearance: /
• Density: 1.571 g/cm³
• Vapor Pressure: 2.19E-05mmHg at 25°C
• Refractive Index: 1.708
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 13.40±0.40(Predicted)
• CAS DataBase Reference: 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE(67139-79-1)
• EPA Substance Registry System: 4,6-DICHLORO-1H-PYRROLO-[3,2-C]-PYRIDINE(67139-79-1)

Safety Data

• Hazardous Substances Data: 67139-79-1(Hazardous Substances Data)

Usage

General Description

4,6-Dichloro-1H-pyrrolo[3,2-c]pyridine, also known as DCPP, is a chemical compound that belongs to the class of pyrrolopyridine derivatives. It is a highly specific and potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), which are enzymes involved in cell cycle regulation. DCPP has shown promising potential as a therapeutic agent for the treatment of various types of cancer, including breast cancer. Its unique mechanism of action makes it a valuable compound for the development of targeted cancer therapies, and it is currently being studied in preclinical and clinical trials for its anti-cancer properties. Furthermore, DCPP has also been investigated for its potential application in other therapeutic areas such as neurodegenerative diseases and inflammatory disorders.

InChI:InChI=1/C7H4Cl2N2/c8-6-3-5-4(1-2-10-5)7(9)11-6/h1-3,10H

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 25194-01-8 4-nitro-2,6-dichloro-pyridine 

Downstream Products

• 1313714-41-8 6-chloro-4-(furan-2-yl)-1-(4-methoxybenzyl)-1H-pyrrolo[3,2-c]pyridine 
• 1313714-54-3 4,6-dichloro-1-(4-methoxybenzyl)-1H-pyrrolo[3,2-c]pyridine 
• 133636-75-6 1-(β-D-arabinofuranosyl)-3-benzyl-4,6-dichloro-1H-pyrrolo<3,2-c>pyridine 
• 120552-24-1 4,6-Dichloro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5'-O-(4,4'-dimethoxytrityl)-3'-O-phenoxythiocarbonyl-1H-pyrrolo<3,2-c>pyridine 
• 120552-23-0 4,6-Dichloro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-5'-O-(4,4'-dimethoxytrityl)-1H-pyrrolo<3,2-c>pyridine 
• 120552-25-2 4,6-Dichloro-1-(2,3-dideoxy-β-D-glycero-pentofuranosyl)-5'-O-(4,4'-dimethoxytrityl)-1H-pyrrolo<3,2-c>pyridine 
• 114915-05-8 4-Amino-6-chloro-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1H-pyrrolo<3,2-c>pyridine 
• 114915-06-9 4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)pyrrolo<3,2-c>pyridine 
• 622380-24-9 4,6-dichloro-1-[3,5-bis-O-(2,4-dichlorophenylmethyl)-2-C-methyl-β-D-ribofuranosyl]-1H-pyrrolo[3,2-c]pyridine 
• 133636-73-4 4,6-dichloro-1-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)-1H-pyrrolo<3,2-c>pyridine 
• 133636-74-5 4,6-dichloro-1-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)-1H-pyrrolo<3,2-c>pyridine 
• 91713-48-3 4,6-Dichloro-1-<2-deoxy-3,5-bis-O-(4-methylbenzoyl)-β-D-erythro-pentofuranosyl>-1H-pyrrolo<3,2-c>pyridine 

Relevant articles and documents

PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE AND THIADIAZOLE DERIVATIVES

Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula (I) can be used as agrochemical active ingredients and can be prepared in a manner known per se.