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4,6-Dichloro-1H-pyrrolo[3,2-c]pyridine, also known as DCPP, is a pyrrolopyridine derivative that serves as a highly specific and potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). These enzymes play a crucial role in cell cycle regulation, and DCPP's ability to inhibit them has positioned it as a promising therapeutic agent for various types of cancer, particularly breast cancer. Its unique mechanism of action and potential in targeted cancer therapies make it a valuable compound for ongoing preclinical and clinical trials, as well as for potential applications in neurodegenerative diseases and inflammatory disorders.

67139-79-1

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67139-79-1 Usage

Uses

Used in Oncology:
4,6-Dichloro-1H-pyrrolo[3,2-c]pyridine is used as an anti-cancer agent for its ability to inhibit CDK4/6, enzymes that are instrumental in the regulation of the cell cycle. By targeting these enzymes, DCPP shows promise in the treatment of various cancer types, with a specific focus on breast cancer. Its potential to be developed into targeted cancer therapies is currently under investigation in preclinical and clinical trials.
Used in Neurodegenerative Disease Research:
DCPP is being explored for its potential application in the treatment of neurodegenerative diseases. Given its role in cell cycle regulation, it may offer insights into the mechanisms underlying these conditions and contribute to the development of novel therapeutic approaches.
Used in Inflammatory Disorder Research:
In addition to its anti-cancer properties, DCPP is also being investigated for its potential in treating inflammatory disorders. The modulation of CDK4/6 by DCPP could have implications for the management of inflammatory processes, and further research is needed to understand its full potential in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 67139-79-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,1,3 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 67139-79:
(7*6)+(6*7)+(5*1)+(4*3)+(3*9)+(2*7)+(1*9)=151
151 % 10 = 1
So 67139-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4Cl2N2/c8-6-3-5-4(1-2-10-5)7(9)11-6/h1-3,10H

67139-79-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,6-Dichloro-1H-pyrrolo[3,2-c]pyridine

1.2 Other means of identification

Product number -
Other names 4,6-dichloro-1H-pyrrolo[3,2-c]pyridine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:67139-79-1 SDS

67139-79-1Relevant academic research and scientific papers

PESTICIDALLY ACTIVE PYRIDYL- AND PYRIMIDYL- SUBSTITUTED THIAZOLE AND THIADIAZOLE DERIVATIVES

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Page/Page column 52, (2013/11/05)

Compounds of formula (I), wherein the substituents are as defined in claim 1, and the agrochemically acceptable salts and all stereoisomers and tautomeric forms of the compounds of formula (I) can be used as agrochemical active ingredients and can be prepared in a manner known per se.

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