67159-34-6Relevant academic research and scientific papers
One-Pot Preparation of Aromatic Amides, 4-Arylthiazoles, and 4-Arylimidazoles from Arenes
Yamamoto, Takahiro,Togo, Hideo
, p. 4187 - 4196 (2018/08/21)
Simple treatment of arenes with α-bromoacetyl chloride and AlCl3, followed by the reaction with molecular iodine and aq. NH3, thioamides, or amidines gave the corresponding primary aromatic amides, 4-arylthiazoles, or 4-arylimidazoles in good yields, respectively. Aryl α-bromomethyl ketones are the key intermediates in those reactions. Primary aromatic amides were formed from arenes through the reaction of aryl α-bromomethyl ketones with molecular iodine and aq. NH3, and 4-arylthiazoles and 4-arylimidazoles were formed from arenes through the reactions of aryl α-bromomethyl ketones with thioamides and amidines, respectively, in one pot under transition-metal-free conditions.
Reactions of Xanthinium N(7)-Ylides with Olefinic Dipolarophiles
Hori, Mikio,Kataoka, Tadashi,Shimizu, Hiroshi,Imai, Eiji,Matsumoto, Yukiharu,et al.
, p. 1211 - 1220 (2007/10/02)
The stereo- and regio-chemical aspects of the reactions of xanthinium N(7)-methylides (2) with olefinic dipolarophiles were elucidated.The reactions of ylides (2) with N-phenylmaleimide afforded stereoselective endo adducts, and with acrylates and acrylon
