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17β-[(Trimethylsilyl)oxy]estr-4-en-3-one is a synthetic organic compound with the molecular formula C21H32O2Si. It is a derivative of estrone, a naturally occurring steroid hormone, and features a trimethylsilyl ether protecting group at the 17β position. This modification is often used in organic synthesis to protect the hydroxyl group from unwanted reactions. The compound is characterized by its ability to stabilize the molecule and prevent side reactions, making it a valuable intermediate in the synthesis of various steroidal compounds and pharmaceuticals. It is typically used in research and development settings for the preparation of more complex steroidal molecules and has applications in the fields of medicine and chemistry.

6717-72-2

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6717-72-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6717-72-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,1 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6717-72:
(6*6)+(5*7)+(4*1)+(3*7)+(2*7)+(1*2)=112
112 % 10 = 2
So 6717-72-2 is a valid CAS Registry Number.

6717-72-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 17β-((Trimethysilyl)oxy)estr-4-en-3-one

1.2 Other means of identification

Product number -
Other names (8R,9S,10R,13S,14S,17S)-13-Methyl-17-trimethylsilanyloxy-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6717-72-2 SDS

6717-72-2Relevant academic research and scientific papers

Convenient Syntheses of Stereoisomeric 1,2-Epoxyestr-4-en-3-ones, Putative Intermediates in Estradiol Metabolism

Menberu, Dirshaye,Nguyen, Phuoc Van,Onan, Kay D.,Quesne, Philip W. Le

, p. 2100 - 2104 (2007/10/02)

New synthetic sequences are described for 17β-hydroxy-1β,2β- and -1α,2α-epoxyestr-4-en-3-one, which are putative intermediates in the metabolism of estradiol to the 2,3- and 3,4-catecholestrogens, as well as the synthetic precursors of choice for these catechols.

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