67173-98-2Relevant academic research and scientific papers
Synthesis and antimicrobial activity of electron rich olefin derived cyclic ureas
Cetinkaya, Bekir,Cetinkaya, Engin,Kuecuekbay, Hasan,Durmaz, Riza
, p. 1154 - 1158 (2007/10/03)
Seventeen cyclic ureas containing imidazolidine and benzimidazoline nuclei were synthesised by the reaction of electron-rich olefins with appropriate group 16 elements (O, S, Se, Te). The compounds synthesised were identified by 1H, 13C-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All compounds studied in this work were screened for their in vitro antimicrobial activity against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 27853). Eight of the compounds were found effective to inhibit the growth of Gram-positive bacteria (Enterococcus faecalis and Staphylococcus aureus) at MIC values between 25-400 μg/ml. None of the compounds exhibit antimicrobial activity against gram-negative bacteria (Escherichia coli and Pseudmonas aeruginosa) at the concentrations studied (6.25-800 μg/ml).
Dication Ethers and Related Compounds, 1. On Dication Chalkogenides and Dichalkogenides
Maas, Gerhard,Singer, Berndt
, p. 3659 - 3674 (2007/10/02)
Reaction of N,N-, N,S-, S,S-, and O,O-substituted thiones 4a-f or selones 6a-c with trifluoromethanesulfonic anhydride leads to dication disulfides 5a-f or diselenides 7a-c, resp.No dication sulfides or selenides are obtained whose formation would parallel the reactivity of the corresponding urea derivatives.This class of dications (14, 15) is, on the other hand, accessible by the reaction of dication ethers 13 with thiones 4 or selones 6. 1H and 13C NMR data of the dication dichalkogenides and chalkogenides are compared with each other.
