671786-77-9Relevant academic research and scientific papers
Synthesis of cyclopropanes via iodine-magnesium exchange between 3-iodomethyl-1-oxacyclopentanes and organomagnesium reagents
Tsuji, Takashi,Nakamura, Tomoaki,Yorimitsu, Hideki,Shinokubo, Hiroshi,Oshima, Koichiro
, p. 973 - 978 (2004)
Iodine-magnesium exchange occurs upon treatment of 3-iodomethyl-1- oxacyclopentanes with alkyl Grignard reagents or trialkylmagnesate. The resulting organomagnesium compounds undergo intramolecular nucleophilic substitution in ether to afford cyclopropane skeletons in a stereoselective manner.
