67191-36-0

Upstream product

• 1779-49-3 Methyltriphenylphosphonium bromide 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 142523-69-1 1-benzyloxy-2-iodobenzene 
• 100-39-0 benzyl bromide 
• 90-02-8 salicylaldehyde 
• 19493-09-5 Methylenetriphenylphosphorane 

Downstream Products

• 908338-99-8 5-(2-benzyloxy-phenyl)-3-(1,4,5,6,8-pentamethoxy-3-triethylsilanyloxy-naphthalen-2-ylmethyl)-4,5-dihydro-isoxazole 
• 908292-06-8 1,4-bis(2-benzyloxyphenyl)-4-hydroxybutan-2-one 
• 1015689-75-4 C₂₁H₂₆OS₂ 
• 7462-25-1 2-(benzyloxy)-1-ethylbenzene 
• 645405-50-1 2-(2-(benzyloxy)phenyl)propanal 

Relevant academic research and scientific papers

SULFAMATE DERIVATIVE COMPOUNDS FOR USE IN TREATING OR ALLEVIATING PAIN

The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically,

Iron-catalyzed olefin hydrogenation at 1 bar H2 with a FeCl3-LiAlH4 catalyst

The scope and mechanism of a practical protocol for the iron-catalyzed hydrogenation of alkenes and alkynes at 1 bar H2 pressure were studied. The catalyst is formed from cheap chemicals (5 mol% FeCl3-LiAlH4, THF). A homogeneous mechanism operates at early stages of the reaction while active nanoparticles form upon ageing of the catalyst solution. This journal is

Chemo-, Regio-, and stereoselective trifluoromethylation of styrenes via visible light-driven single-electron transfer (SET) and triplet-triplet energy transfer (TTET) processes

A process for tunable and chemo-, regio-, and stereoselective photocatalytic trifluoromethylation of styrenes was developed. Thermodynamically stable E-trifluoromethylated alkenes were prepared using Tognis reagent in the presence of Ru(bpy)3Cl2·6H2O under visible light irradiation, whereas less thermodynamically stable Z-trifluoromethylated alkenes were obtained by employing Umemotos reagent and photocatalyst Ir(ppy)3.

Efficient heterogeneous vinylation of aryl halides using potassium vinyltrifluoroborate

An efficient heterogeneously palladium catalysed procedure for the vinylation of aryl iodides and bromides is reported. Using common reaction conditions (Pd/C 2 mol %, AcONa·3H2O, NMP or NMP/H2O), good to complete conversions (40-100%) with high selectivities (79-100%) towards the expected vinylaromatic were achieved.

β-Hydroxy-α-tosyloxy esters as chiral building blocks for the enantioselective synthesis of benzo-annulated oxa-heterocycles: scope and limitations

The enantioselective synthesis of benzo-annulated oxa-heterocycles 2,3-dihydrobenzofuran and 1-benzopyran derivatives is described using β-hydroxy-α-tosyloxy esters as chiral building blocks, which are easily accessible through the regioselective α-tosyla

Asymmetric synthesis of 3,4-dihydrocoumarins by rhodium-catalyzed reaction of 3-(2-hydroxyphenyl)cyclobutanones

3,4-Dihydrocoumarin derivatives were synthesized in a highly enantioselective manner from 3-(2-hydroxyphenyl)cyclobutanones through enantioselective carbon-carbon bond cleavage. A cascade reaction with electron-deficient alkenes introduced a carbon-carbon

Probing of the ligand anatomy: Effects of the chelating alkoxy ligand modifications on the structure and catalytic activity of ruthenium carbene complexes

Structural modifications of the Hoveyda-Grubbs ruthenium metathesis complex via electronic and structural withdrawing of the chelating alkoxy ligand were investigated. By decreasing the donor properties of the oxygen atom, an acceleration in catalytic act

Convergent route to the purpuromycin bisphenolic spiroketal: hydrogen bonding control of spiroketalization stereochemistry

A mild and efficient [3+2] nitrile oxide/olefin cycloaddition provided a rapid and convergent entry into precursors of bisphenolic spiroketals, a structural type unique to the rubromycin family of natural products. In addition, implementation of the premi

Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists

A series of novel ortho-substituted cinnamic acids have been synthesized, and their binding activity and selectivity on the four prostaglandin E 2 receptors evaluated. Many of them are very potent and selective EP3 antagonists (Ki 3-10 nM), while compound 9 is a very good and selective EP2 agonist (Ki 8 nM). The biological profile of the EP2 agonist 9 in vivo and the metabolic profile of selected EP3 antagonists are also reported.