67198-88-3

Upstream product

• 67198-87-2 N-t-butyloxycarbonyl D-homoserine sodium salt 
• 776-74-9 Bromodiphenylmethane 
• 908093-98-1 diazodiphenylmethane 
• 7536-55-2 N-t-butyloxycarbonyl-D-asparagine 
• 88147-56-2 N-t-butyloxycarbonyl-D-asparagine, benzhydrylester 
• 88147-57-3 BOC-D-aspartic acid 1-diphenylmethyl ester 
• 67198-86-1 (R)-2-[(tert-butoxycarbonyl)amino]butano-4-lactone 

Downstream Products

• 67529-87-7 -propoxy>phenyl>glyoxylic acid 
• 67198-78-1 (R)-2-tert-Butoxycarbonylamino-4-[4-(4-nitro-benzyloxyoxalyl)-phenoxy]-butyric acid benzhydryl ester 
• 73888-92-3 diphenylmethyl D-4-(p-acetylphenoxy)-2-(1-t-butoxyformamido)butyrate 

Relevant academic research and scientific papers

A total synthesis of nocardicins

Four-component-condensation of D-isoserine or L-isoserine, diphenylmethyl isocyanide and p-(benzyloxy)benzaldehyde was used to construct a functionalized β-lactam ring system which was transformed in 4 steps into 3-aminocardicinic acid. A protected side c

Process for 4-(D-3-amino-3-carboxypropoxy)-phenylglyoxylic acid oxime derivatives

Process for 4-(D-3-amino-3-carboxypropoxy)phenylglyoxylic acid oxime as an amino-protected ester comprising alkylating an amino-protected D-methionine silyl ester with an alkyl or benzyl iodide; cyclizing the alkylsulfonium iodide to an amino-protected D-homoserine lactone; hydrolyzing the lactone to an amino-protected D-homoserine in aqueous base; coupling, to form an ether, the amino-protected D-homoserine as an ester with an ester of 4-hydroxyphenylglyoxylic acid; and forming the oxime of the ether or alternatively coupling the D-homoserine ester with a protected-oxime of an esterified 4-hydroxyphenylglyoxylic acid. The product is useful in preparing the antibiotic FR 1923.