67205-53-2 Usage
Uses
Used in Pharmaceutical Industry:
2,3,5,6-tetrachloro-4-cyanophenyl propanoate serves as a crucial intermediate in the production of pharmaceutical compounds. Its unique structure allows for the development of drugs with specific therapeutic properties, making it valuable in the synthesis of medicinal agents.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,5,6-tetrachloro-4-cyanophenyl propanoate is utilized as an intermediate for the synthesis of pesticides and other crop protection agents. Its chemical properties contribute to the creation of effective solutions for managing pests and diseases in agriculture.
Safety and Environmental Considerations:
Given the high toxicity of 2,3,5,6-tetrachloro-4-cyanophenyl propanoate, it is imperative that strict safety measures are adhered to during its handling, use, and disposal. This includes the use of personal protective equipment to prevent skin and eye contact, as well as careful disposal methods to minimize environmental contamination and protect aquatic ecosystems.
Check Digit Verification of cas no
The CAS Registry Mumber 67205-53-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,2,0 and 5 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67205-53:
(7*6)+(6*7)+(5*2)+(4*0)+(3*5)+(2*5)+(1*3)=122
122 % 10 = 2
So 67205-53-2 is a valid CAS Registry Number.
67205-53-2Relevant academic research and scientific papers
Synthesis and antiinflammatory evaluation of substituted isophthalonitriles, trimesonitriles, benzonitriles, and terephthalonitriles
Heilman,Battershell,Pyne,Goble,Magee
, p. 906 - 913 (2007/10/06)
In an effort to develop nonacidic, nonsteroidal, antiinflammatory agents without gastrointestinal complications, a series of cyanobenzenes was synthesized for antiinflammatory evaluation. Twenty-seven substituted isophthalonitriles, 19 trimesonitriles, 30 benzonitriles, and 16 terephthalonitriles were tested in the rat utilizing the carrageenan-induced pedal edema assay. Based on the performance of phenylbutazone in this assay (43.8% reduction at 100 mg/kg), six compounds, dosed at 50 mg/kg, produced reductions in inflammation comparable to this standard. However, the LD50 value of each compound dosed at this level was in the range of 40-56 mg/kg in the mouse; therefore, further study was not warranted. Fifteen compounds possessed activity in excess of 20% reduction at 200 mg/kg and also possessed LD50 values greater than 300 mg/kg. Of these cyanobenzenes, trimesonitrile, 4-chlorobenzonitrile, 2-chloroterephthalonitrile, and 2-fluoroterephthalonitrile with reductions in edema of 32, 30, 46, and 49%, respectively, represent the best candidates for subsequent study.
