672303-41-2Relevant academic research and scientific papers
LiClO4-Activated stereo- and regioselective alkylation of aldehydes
Markert,Buchem,Krüger,Mahrwald
, p. 993 - 999 (2004)
Aldehydes undergo an unusual and very mild alkylation by LiClO 4-activation in the presence of acids. This new methodology enables the inclusion of a broad range of aldehydes as well as tertiary alcohols. Regio- and stereoselectivity observed during this reaction will be discussed.
A new approach to 2,2-disubstituted chromenes and tetrahydroquinolines through intramolecular cyclization of chiral 3,4-epoxy alcohols
Goujon, Jean-Yves,Zammattio, Fran?oise,Chrétien, Jean-Mathieu,Beaudet, Isabelle
, p. 4037 - 4049 (2007/10/03)
An efficient route to chiral chromene and tetrahydroquinoline ring models 3 and 4 was developed by means of the vanadium epoxidation of chiral homoallylic alcohols 12 and 19 followed by an intramolecular epoxide opening of 3,4-epoxy alcohols 14 and 20. Th
