672307-46-9

Upstream product

• 65632-62-4 (3S)-hexahydro-1,3-pridazinedicarboxylic acid 1-(phenylmethyl) ester 
• 87694-52-8 tert-butyl (S)-1-(N-methoxy-N-methylcarbamoyl)-2-methylpropylcarbamate 
• 4509-90-4 5-bromovaleroyl chloride 
• 628-46-6 5-methylhexanoic acid 
• 5699-78-5 5-methylhexanoyl chloride 
• 672307-45-8 1-(phenylmethyl) hydrogen (3S)-2-[(2R)-2-[2-(1,1-dimethylethoxy)-2-oxoethyl]-5-methyl-1-oxohexyl]hexahydro-1,3-pyridazinedicarboxylate 
• 672307-39-0 4-(1,1-dimethylethyl) hydrogen (2R)-2-(3-methylbutyl)butane-1,4-dioate 
• 672307-42-5 (S)-1-(1-methylethyl)-2-oxobutylcarbamic acid 1,1-dimethylethyl ester 
• 672307-41-4 phenylmethyl (3S)-hexahydro-3-[[(4S)-2-oxo-4-(phenylmethyl)-3-oxazolidinyl]carbonyl]-1-pyridazinecarboxylate 
• 672307-38-9 1,1-dimethylethyl (R)-3-(3-methylbutyl)-4-oxo-4-[(4S)-4-(phenylmethyl)oxazolidin-3-yl]butanoate 
• 672307-37-8 (4S)-3-(5-methyl-1-oxohexyl)-4-(phenylmethyl)-2-oxazolidinone 
• 672307-44-7 1,1-dimethylethyl (3R)-3-(fluorocabonyl)-6-methylheptanoate 
• 156699-38-6 (4S)-3-<(3S)-N,N'-bis(t-butoxycarbonyl)hexahydropyridazine-3-carboxy>-4-phenylmethyl-2-oxazolidinone 
• 156699-39-7 (3S)-N,N'-bis-(t-butoxycarbonyl)hexahydropyridazine-3-carboxylic acid 

Downstream Products

• 672307-47-0 (S)-2-((R)-2-Carboxymethyl-5-methyl-hexanoyl)-3-((S)-1-isopropyl-2-oxo-butylcarbamoyl)-tetrahydro-pyridazine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Stereochemical Definition and Chirospecific Synthesis of the Peptide Deformylase Inhibitor Sch 382583

The recently reported natural product Sch 382583 (1), an inhibitor of peptide deformylase, has been synthesized in 16 steps from commercially available starting materials. The three chiral centers were set by a combination of chiral auxiliary and chiral p