67231-69-0Relevant academic research and scientific papers
Synthesis of new bis-iminocoumarins by Schmidt reaction catalyzed by ion-exchange resins
Ammar, Houcine,Fakhfakh, Mehdi,Le Bigot, Yves,El Gharbi, Rachid
, p. 1821 - 1828 (2003)
A new synthetic route to bis-iminocoumarins is proposed which involves the synthesis of iminocoumarins from reaction of 2-hydroxybenzaldehydes with arylacetonitriles and their coupling with aromatic diamines. Ion-exchange resins were used as catalysts in
Copper-Catalyzed Imino C-N Bond Formation with Aryl Boronic Acids under Aerobic Conditions
Mandal, Prashant S.,Kumar, A. Vijay
supporting information, p. 1408 - 1412 (2016/06/01)
A copper-catalyzed, ligand- and base-free C-N cross-coupling reaction of iminochromenes with arylboronic acids in a nontoxic ethanol solvent at room temperature under air is developed. The product yields are found to be good to moderate. The conservation of the sensitive imine functional group implies the mildness of this protocol.
Iminocoumarin based fluorophores: Indispensable scaffolds for rapid, selective and sensitive detection of thiophenol
Kand, Dnyaneshwar,Mandal, Prashant Sahebrao,Datar, Avdhoot,Talukdar, Pinaki
, p. 25 - 31 (2014/04/03)
Off-on fluorescence probes for the detection of thiophenol were designed based on the reaction mechanism to ensure rapid sensing process. 2,4-Dinitrophenylsulfonyl based probes with iminocoumarin fluorophores were validated by theoretical calculations for their off-fluorescence states. Reaction of these probes with thiophenol released strong fluorescent iminocoumarin species with good response times. These results, upon comparing with reported probes, confirmed that higher pKaH values of the imino nitrogen of iminocoumarins are important for rapid sensing process. Reactivity of these probes was limited to only thiophenol and no reaction was observed with aliphatic thiols. The benzothiazole substituted probe displayed up to 260-fold fluorescence enhancement upon reaction with thiophenol. Sensing of the analyte by the probe was characterized by change in color from red to yellow and with appearance of the green fluorescence. A detection limit up to 6.9 × 10-9 M was also determined for this probe.
Novel synthesis of bis-iminocoumarins
Ammar,Abid,Le Bigot,El Gharbi
experimental part, p. 799 - 810 (2012/01/17)
Reaction of 3-aryl iminocoumarins with diacid chlorides as C-electrophilic reagents under mild conditions novel bis-iminocoumarins in good yields. When the reaction was performed with alkylene dibromides by heating them in toluene in the presence of IRA 9
Polymer supported reagents: Novel methodology for selective and general synthesis of iminocoumarins
Mhiri,El Gharbi,Le Bigot
, p. 3385 - 3399 (2007/10/03)
A selective synthesis of iminocoumarins 3 was accomplished, starting from salicylaldehydes 1 and nitriles 2, by the use of Amberlite IRA 900 resin as a polymeric solid support. The possibility of using various arylacetonitriles enhances the synthetic vers
