672341-49-0

Upstream product

• 587003-81-4 2,2-dimethyl-5-(morpholin-4-yl)-10-thioxo-1,4,10,11-tetrahydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-8(9H)-one 
• 204775-60-0 1-amino-8,8-dimethyl-5-morpholin-4-yl-8,9-dihydro-6H-pyrano[4,3-d]thieno[2,3-b]pyridine-2-carboxamide 

Downstream Products

• 1416039-38-7 C₂₆H₂₆N₆O₂S₂ 
• 1416039-26-3 5-benzylthio-8,8-dimethyl-11-morpholin-4-yl-7,10-dihydro-8H-pyrano[4'',3'':4',5']-pyrido[3',2':4,5]thieno-[2,3-e] [1, 2, 4]triazolo[4,3-c]pyrimidine 
• 1416039-19-4 10-benzylthio-8-hydrazino-2,2-dimethyl-5-morpholin-4-yl-1,4-dihydro-2H-pyrano-[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidine 
• 578751-66-3 10-benzylsulfanyl-8-chloro-2,2-dimethyl-5-(morpholin-4-yl)-1,4-dihydro-2H-pyrano[4'',3'':4',5']pyrido[3',2':4,5]thieno[3,2-d]pyrimidine 

Relevant academic research and scientific papers

Synthesis of 10-alkylsulfanyl-substituted pyrido-[4’,3’:4,5]thieno[3,2-d]pyrimidines annulated with pyran, cyclohexane, and cyclopentane rings

(Formula Presented) We propose a single-step procedure for the synthesis of 8-oxo-10-sulfanylpyrido[4’,3’:4,5]thieno[3,2-d]pyrimidines, annulated with pyran, cyclohexane, or cyclopentane rings. The alkylation of these compounds in aqueous DMF solution of KOH at room temperature was shown to proceed regioselectively and led to the formation of S-substituted products. Amino-and alkoxy-substituted derivatives of tetracyclic thieno[3,2-d]pyrimidines were synthesized. The antimicrobial activity of the obtained compounds was studied on Grampositive staphylococci and Gram-negative rods.