67253-01-4

Usage

Uses

Used in Pharmaceutical Industry:
Cabraleadiol is used as a potential medicinal compound for its antifungal and antiparasitic activities. It is being studied for its ability to combat various fungal and parasitic infections due to its inherent biological properties.
Used in Anti-Inflammatory Applications:
Cabraleadiol is used as an anti-inflammatory agent, potentially beneficial in reducing inflammation and associated symptoms in various conditions. Its anti-inflammatory properties are under investigation for their therapeutic potential.
Used in Antioxidant Applications:
Cabraleadiol is used as an antioxidant agent, which may help protect cells from damage caused by free radicals and oxidative stress. Its antioxidant capabilities are being explored for their potential role in preventing or treating diseases associated with oxidative stress.
Used in Drug Development:
Cabraleadiol is used as a molecule for further pharmaceutical research and development, given its promising medicinal properties and unique chemical structure. It may lead to the creation of new drugs for various therapeutic applications.

InChI:InChI=1/C30H52O3/c1-25(2)21-12-17-29(7)22(27(21,5)15-13-23(25)31)10-9-19-20(11-16-28(19,29)6)30(8)18-14-24(33-30)26(3,4)32/h19-24,31-32H,9-18H2,1-8H3/t19-,20+,21+,22-,23-,24+,27+,28-,29-,30+/m1/s1

Upstream product

• 35833-62-6 20S,24S-epoxydammarane-25-ol-3α-yl acetate 
• 35761-54-7 25-hydroxy-(20S,24S)-epoxydammaran-3-one 
• 5986-39-0 3-epiocotillol 
• 19132-84-4 ocotillone 

Downstream Products

• 19865-87-3 cabralelactone 
• 35833-62-6 20S,24S-epoxydammarane-25-ol-3α-yl acetate 
• 5244-35-9 Acetic acid (3R,5R,8R,9R,10R,14R,17S)-17-[(2S,5R)-5-(1-hydroxy-1-methyl-ethyl)-2-methyl-tetrahydro-furan-2-yl]-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 
• 19132-84-4 ocotillone 
• 5986-39-0 ocotillol 
• 5244-35-9 Acetic acid (3S,5R,8R,9R,10R,14R,17S)-17-[(2S,5R)-5-(1-hydroxy-1-methyl-ethyl)-2-methyl-tetrahydro-furan-2-yl]-4,4,8,10,14-pentamethyl-hexadecahydro-cyclopenta[a]phenanthren-3-yl ester 

Relevant academic research and scientific papers

A pregnane steroid from Aglaia lawii and structure confirmation of cabraleadiol monoacetate by X-ray crystallography

The pregnane steroid, (E)-aglawone, along with four known triterpenes, and a known sterol mixture were isolated from the bark of Aglaia lawii (Wight) Saldanha ex Ramamoorty (Meliaceae). The structural determination/identification was accomplished by a combination of 1D- and 2D-NMR spectroscopic techniques. The relative stereochemistry of the known triterpene, 20S,24S-epoxydammarane-3α, 25-diol acetate, was also unequivocally determined for the first time by X-ray crystallography. The isolates were not active against various human cancer cell lines.

DAMMARANE TRITERPENES FROM THE STEM BARK OF COMMIPHORA DALZIELLI

From the stem bark of Commiphora dalzielii the isolation and identification of the 20,24-epoxydammarane triterpenes cabraleadiol 3-acetate, cabraleadiol and cabraleone and isofouquierone are reported.Both the acetate and isofouquierone appear to be novel.The chemotaxonomic implications of findings this type of triterpene in the Burseraceae are discussed.Key Word Index - Commiphora dalzielii; Burseraceae; dammaranes; cabraleadiol; cabraleadiol 3-acetate; cabraleone; isofouquierone; chemical taxonomy.

TRITERPENOIDS FROM THE LEAVES OF Betula lanata

From the unsaponifiable fraction of an ethereal extract of the leaves of Betula lanata, in addition to 3-epiocotillol (I) we have isolated a new triterpene, 20(S),24(R)-epoxydammarane-3α,11α,25-triol (V) and also derivatives of it - the monoacetates at C-3 (II) and C-11 (III), and the monoketone at C-3 (IV).The structures of compounds (I-V) have been established on the basis of the results of physicochemical investigations.